ArticleAntimicrobial agents and chemotherapy2012
Inhibition of Staphylococcus epidermidis biofilm by trimethylsilane plasma coating.
Article in Antimicrobial agents and chemotherapy, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
24 citing papers in PubMed, 75 citations in OpenAlex.
- Antimicrobial Coatings Based on a Photoreactive (Meth)acrylate Syrup and Ferulic Acid-The Effectiveness againstPolymers · 2024Article
- In vitro biological responses of plasma nanocoatings for coronary stent applications.Journal of biomedical materials research. Part A · 2023Article
- Microbial Biofilm: A Review on Formation, Infection, Antibiotic Resistance, Control Measures, and Innovative Treatment.Microorganisms · 2023Review
- Review
- Bacteriostatic Poly Ethylene Glycol Plasma Coatings for Orthodontic Titanium Mini-Implants.Materials (Basel, Switzerland) · 2022Article
- Plasma SiOx:H Nanocoatings to Enhance the Antibacterial and Anti-Inflammatory Properties of Biomaterials.International journal of nanomedicine · 2022Article
- Biofilms: Formation, drug resistance and alternatives to conventional approaches.AIMS microbiology · 2022Review
- Cold plasma surface treatments to prevent biofilm formation in food industries and medical sectors.Applied microbiology and biotechnology · 2022Review
- Phage φAB6-Borne Depolymerase CombatsAntibiotics (Basel, Switzerland) · 2021Article
- Physicochemical properties and formulation development of a novel compound inhibiting Staphylococcus aureus biofilm formation.PloS one · 2021Article
- Characteristics of oral methicillin-resistant Staphylococcus epidermidis isolated from dental plaque.International journal of oral science · 2020Article
- The Effects of Titanium Surfaces Modified with an Antimicrobial Peptide GL13K by Silanization on Polarization, Anti-Inflammatory, and Proinflammatory Properties of Macrophages.BioMed research international · 2020Article
- Sepsis: mechanisms of bacterial injury to the patient.Scandinavian journal of trauma, resuscitation and emergency medicine · 2019Review
- AnJournal of oral microbiology · 2019Article
- Current therapies in treatment and prevention of fracture wound biofilms: why a multifaceted approach is essential for resolving persistent infections.Journal of bone and joint infection · 2018Review
- Effects of trimethylsilane plasma coating on the hydrophobicity of denture base resin and adhesion of Candida albicans on resin surfaces.The Journal of prosthetic dentistry · 2017Article
- In vivo bactericidal efficacy of the Ti6Al4V surface after ultraviolet C treatment.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2017Article
- Electrochemical study on the corrosion resistance of plasma nanocoated 316L stainless steel in albumin- and lysozyme-containing electrolytes.Current topics in electrochemistry · 2017Article
- An investigation of the antibacterial ability and cytotoxicity of a novel cu-bearing 317L stainless steel.Scientific reports · 2016Article
- Nanoscale Plasma Coating Inhibits Formation of Staphylococcus aureus Biofilm.Antimicrobial agents and chemotherapy · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Biofilm formation on implantable medical devices is a major impediment to the treatment of nosocomial infections and promotes local progressive tissue destruction. Staphylococcus epidermidis infections are the leading cause of biofilm formation on indwelling devices. Bacteria in biofilms are highly resistant to antibiotic treatment, which in combination with the increasing prevalence of antibiotic resistance among human pathogens further complicates treatment of biofilm-related device infections. We have developed a novel plasma coating technology. Trimethylsilane (TMS) was used as a monomer to coat the surfaces of 316L stainless steel and grade 5 titanium alloy, which are widely used in implantable medical devices. The results of biofilm assays demonstrated that this TMS coating markedly decreased S. epidermidis biofilm formation by inhibiting the attachment of bacterial cells to the TMS-coated surfaces during the early phase of biofilm development. We also discovered that bacterial cells on the TMS-coated surfaces were more susceptible to antibiotic treatment than their counterparts in biofilms on uncoated surfaces. These findings suggested that TMS coating could result in a surface that is resistant to biofilm development and also in a bacterial community that is more sensitive to antibiotic therapy than typical biofilms.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.