SynthesisScandinavian journal of trauma, resuscitation and emergency medicine2012
Systematic review of predictive performance of injury severity scoring tools.
Synthesis in Scandinavian journal of trauma, resuscitation and emergency medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06705959 (Can NISS or ISS Better Predict Mortality in Blunt Trauma Patients? A Prospective Study), which is not on this map. Cited by 72 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Can NISS or ISS Better Predict Mortality in Blunt Trauma Patients? A Prospective Study
Who cites it
72 citing papers in PubMed, 1 synthesis or guideline pooled it, 149 citations in OpenAlex.
- Comparison of the Ability to Predict Mortality between the Injury Severity Score and the New Injury Severity Score: A Meta-Analysis.International journal of environmental research and public health · 2016Pooled it
- Evaluating and Updating the IMPACT Model to Predict Outcomes in Two Contemporary North American Traumatic Brain Injury Cohorts.Journal of neurotrauma · 2025Trial
- Characterization of unexpected survivors following a prehospital plasma randomized trial.The journal of trauma and acute care surgery · 2020Trial
- Article
- Advancing trauma scoring through large language models: automated estimation of injury severity.BMC emergency medicine · 2026Article
- Article
- Predictive Value of Systemic Immune-Inflammation Index Combined with D-Dimer Levels and Injury Severity Score for the Prognosis of Patients with Multiple Injuries: A Retrospective Analysis.Open access emergency medicine : OAEM · 2026Article
- Lactate dehydrogenase-to-albumin ratio as a novel prognostic biomarker for 28-day mortality in thoracic trauma: a single-center retrospective cohort study.Turkish journal of medical sciences · 2026Observational
- External Validation of the Trauma Early Mortality Prediction Tool (TEMPT) in an Iranian Trauma Population.Medical journal of the Islamic Republic of Iran · 2026Article
- International Classification of Disease based Injury Severity Score (ICISS): a comparison of methodologies applied to linked data from New South Wales, Australia.Injury prevention : journal of the International Society for Child and Adolescent Injury Prevention · 2025Article
- Comparison of Esketamine and Propofol for Prehospital Emergency Anaesthesia in Patients With Traumatic Brain Injury-A Retrospective Observational Study.Acta anaesthesiologica Scandinavica · 2025Observational
- Wedge fragments: no significant impact on bone healing in femoral shaft fractures treated with intramedullary nailing.Archives of orthopaedic and trauma surgery · 2025Article
- Development of a severity score based on the International Classification of Disease-10 for general patients visiting emergency centers.BMC emergency medicine · 2025Article
- Predictive factors of mortality in patients with abdominal trauma.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2025Article
- 30-day survival and injury severity in traffic accidents in Iran: A mixed-method study protocol.PloS one · 2025Article
- Efficacy of the Geriatric Trauma Outcome Score (GTOS) in Predicting Mortality in Trauma Patients: A Retrospective Cross-Sectional Study.Diagnostics (Basel, Switzerland) · 2024Article
- Minor trauma and venous thromboembolism: the threshold for antithrombotic prophylaxis.Haematologica · 2024Review
- Prognostic indicators in patients with isolated thoracic trauma: A retrospective cross-sectional study.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2024Article
- Evaluation of traumatic spinal injuries: a pediatric perspective.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Article
- Comparison of Scoring Systems for Mortality Prediction in Pediatric Multitrauma Patients.Journal of pediatric intensive care · 2024Article
12 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Many injury severity scoring tools have been developed over the past few decades. These tools include the Injury Severity Score (ISS), New ISS (NISS), Trauma and Injury Severity Score (TRISS) and International Classification of Diseases (ICD)-based Injury Severity Score (ICISS). Although many studies have endeavored to determine the ability of these tools to predict the mortality of injured patients, their results have been inconsistent. We conducted a systematic review to summarize the predictive performances of these tools and explore the heterogeneity among studies. We defined a relevant article as any research article that reported the area under the Receiver Operating Characteristic curve as a measure of predictive performance. We conducted an online search using MEDLINE and Embase. We evaluated the quality of each relevant article using a quality assessment questionnaire consisting of 10 questions. The total number of positive answers was reported as the quality score of the study. Meta-analysis was not performed due to the heterogeneity among studies. We identified 64 relevant articles with 157 AUROCs of the tools. The median number of positive answers to the questionnaire was 5, ranging from 2 to 8. Less than half of the relevant studies reported the version of the Abbreviated Injury Scale (AIS) and/or ICD (37.5%). The heterogeneity among the studies could be observed in a broad distribution of crude mortality rates of study data, ranging from 1% to 38%. The NISS was mostly reported to perform better than the ISS when predicting the mortality of blunt trauma patients. The relative performance of the ICSS against the AIS-based tools was inconclusive because of the scarcity of studies. The performance of the ICISS appeared to be unstable because the performance could be altered by the type of formula and survival risk ratios used. In conclusion, high-quality studies were limited. The NISS might perform better in the mortality prediction of blunt injuries than the ISS. Additional studies are required to standardize the derivation of the ICISS and determine the relative performance of the ICISS against the AIS-based tools.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.