Evidence map›Paper›PMID 22963934›Full record

ArticleThe international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease2012

Alcohol use and abuse among patients with multidrug-resistant tuberculosis in Botswana.

N M Zetola, C Modongo, E C Kip, R Gross, G P Bisson, R G Collman

Abstract read
In one paragraph

Article in The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  12. Mental health research in Botswana: a semi-systematic scoping review.The Journal of international medical research · 2020
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  18. The joint impact of smoking plus alcohol drinking on treatment of pulmonary tuberculosis.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

N M ZetolaDivision of Infectious Diseases, University of Pennsylvania, Philadelphia, Pennsylvania, USA. nzetola@hotmail.com
C Modongo
E C Kip
R Gross
G P Bisson
R G Collman

Funding

Virus & Reservoirs CoreP30AI045008 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI ROBERT GROSS · 1999 to 2026
$78.6M
Dynamics of TB and MDR TB transmission in areas with high HIV prevalenceR01AI097045 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI ZETOLA, NICOLA MARIO · 2011 to 2015
$2.9M
NIAID NIH HHS P30 AI045008NIAID NIH HHS P30AI45008NIAID NIH HHS R01 AI097045
6 · The paper itself

Abstract

backgroundData on alcohol abuse as a risk factor for the development of multidrug-resistant tuberculosis (MDR-TB) are scarce.

objectiveTo describe the patterns of alcohol use in MDR-TB patients and to determine whether alcohol use is associated with the development of MDR-TB in Botswana.

methodsWe compared the level of alcohol use among MDR-TB patients against three control groups: 1) non-MDR-TB patients, 2) human immunodeficiency virus (HIV) infected patients without a history of TB, and 3) the general population. Alcohol use and abuse was measured with the Alcohol Use Disorders Identification Test 10 (AUDIT) questionnaire.

resultsOf a total national population of 164 MDR-TB cases, 114 (70%) were interviewed. MDR-TB cases had a lifetime prevalence of alcohol use of 35.1%, which was lower than that of all control groups (P < 0.001). MDR-TB cases had higher 1-month prevalence of alcohol dependence symptoms and a lower 1-year period prevalence of alcohol dependence symptoms (P < 0.01 and P = 0.01 respectively). Among patients with TB, alcohol abuse was found to be a risk factor for the development of MDR-TB.

conclusionMDR-TB patients in Botswana have high rates of alcohol use and abuse. Among TB patients, alcohol abuse is associated with the diagnosis of MDR-TB, and could be an important modifiable factor.

Indexed as

AdultAlcohol DrinkingAlcoholismBotswanaCase-Control StudiesHIV InfectionsHumansMaleMiddle AgedPrevalenceRisk FactorsSurveys and QuestionnairesTuberculosisTuberculosis, Multidrug-ResistantYoung Adult

Identifiers

PMID22963934
PMCPMC3730124

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.