Trial reportBMC neuroscience2012
Enhancement of object detection with transcranial direct current stimulation is associated with increased attention.
Trial report in BMC neuroscience, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02780739 (An Integrative System for Enhancing Fluid Intelligence), which is not on this map. Cited by 55 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
An Integrative System for Enhancing Fluid Intelligence (Gf) Through Human Cognitive Activity, Fitness, High-definition Transcranial Direct-current Brain Stimulation (HD-tDCS), and Nutritional Intervention
Who cites it
55 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Efficacy of non-invasive brain stimulation on cognitive and motor functions in multiple sclerosis: A systematic review and meta-analysis.Frontiers in neurology · 2023Pooled it
- Concurrent tDCS-fMRI after stroke reveals link between attention network organization and motor improvement.Scientific reports · 2024Trial
- Attention neuroenhancement through tDCS or neurofeedback: a randomized, single-blind, controlled trial.Scientific reports · 2022Trial
- Polarity-dependent cerebellar transcranial direct current stimulation modulates online functions of the alerting attention network.Neurosciences (Riyadh, Saudi Arabia) · 2021Trial
- Cognitive function assessment during 2 mA transcranial direct current stimulation in DLPFC in healthy volunteers.Physiological reports · 2019Trial
- The Cerebellum Modulates Attention Network Functioning: Evidence from a Cerebellar Transcranial Direct Current Stimulation and Attention Network Test Study.Cerebellum (London, England) · 2019Trial
- Transcranial direct current stimulation (tDCS) over right temporoparietal junction (rTPJ) for social cognition and social skills in adults with autism spectrum disorder (ASD).Journal of neural transmission (Vienna, Austria : 1996) · 2018Trial
- Neurophysiological Evidence of Enhanced Cognitive Control Following Auditory Control Enhancement (ACE) Therapy: A Pilot RCT in Schizophrenia-Spectrum Disorders with Persistent Auditory Hallucinations.Clinical EEG and neuroscience · 2026Article
- A causal and dissociable role for the right inferior frontal gyrus in empathy for physical and social pain.Cognitive, affective & behavioral neuroscience · 2026Article
- The Modulatory Effect of tDCS Onset Timing in Alleviating Vigilance Decrement.Brain sciences · 2025Article
- Breath-Counting Task Enhances the Sensitivity of Fear Acquisition.Behavioral sciences (Basel, Switzerland) · 2025Article
- Closed-Loop Auditory Stimulation (CLAS) During Sleep Augments Language and Discovery Learning.Brain sciences · 2024Article
- Frequency-specific static and dynamic neural activity indices in children with different attention deficit hyperactivity disorder subtypes: a resting-state fMRI study.Frontiers in human neuroscience · 2024Article
- The distinct and potentially conflicting effects of tDCS and tRNS on brain connectivity, cortical inhibition, and visuospatial memory.Frontiers in human neuroscience · 2024Article
- High-Definition Transcranial Direct Current Stimulation in the Right Ventrolateral Prefrontal Cortex Lengthens Sustained Attention in Virtual Reality.Bioengineering (Basel, Switzerland) · 2023Article
- Closed-Loop tACS Delivered during Slow-Wave Sleep Reduces Retroactive Interference on a Paired-Associates Learning Task.Brain sciences · 2023Article
- Combined Bifrontal Transcranial Direct Current Stimulation and Auditory Stroop Training in Chronic Tinnitus.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023Article
- Anodal transcranial direct current stimulation (tDCS) over the left dorsolateral prefrontal cortex improves attentional control in chronically stressed adults.Frontiers in neuroscience · 2023Article
- Failure of tDCS to impact militarised threat-detection in a military cohort.Imaging neuroscience (Cambridge, Mass.) · 2023Article
- Effects of transcranial direct current stimulation (tDCS) in "Kiss nightclub fire" patients with post-traumatic stress disorder (PTSD): A phase II clinical trial.SAGE open medicine · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe previously found that Transcranial Direct Current Stimulation (tDCS) improves learning and performance in a task where subjects learn to detect potential threats indicated by small target objects hidden in a complex virtual environment. In the present study, we examined the hypothesis that these effects on learning and performance are related to changes in attention. The effects of tDCS were tested for three forms of attention (alerting, orienting, and executive attention) using the Attention Network Task (ANT), which were compared with performance on the object-learning task.
resultsParticipants received either 0.1 mA (N = 10) or 2.0 mA (N = 9) tDCS during training and were tested for performance in object-identification before training (baseline-test) and again immediately after training (immediate test). Participants next performed the Attention Networks Task (ANT), and were later tested for object-identification performance a final time (delayed test). Alerting, but not orienting or executive attention, was significantly higher for participants receiving 2.0 mA compared with 0.1 mA tDCS (p < 0.02). Furthermore, alerting scores were significantly correlated with the proportion of hits (p < 0.01) for participants receiving 2.0 mA.
conclusionsThese results indicate that tDCS enhancement of performance in this task may be related in part to the enhancement of alerting attention, which may benefit the initial identification, learning and/or subsequent recognition of target objects indicating potential threats.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.