Trial reportThe international journal of behavioral nutrition and physical activity2012
Effects of a 6-month multimodal training intervention on retention of functional fitness in older adults: a randomized-controlled cross-over design.
Trial report in The international journal of behavioral nutrition and physical activity, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 72 citations in OpenAlex.
- Agility performance in healthy older adults is associated with handgrip strength and force development: results from a 1-year randomized controlled trial.European geriatric medicine · 2023Trial
- Comprehensive Time-Course Effects of Combined Training on Hypertensive Older Adults: A Randomized Control Trial.International journal of environmental research and public health · 2022Trial
- The Effects of 32 Weeks of Multicomponent Training with Different Exercises Order in Elderly Women's Functional Fitness and Body Composition.Medicina (Kaunas, Lithuania) · 2022Trial
- Maintenance of Physical Function 1 Year After Exercise Intervention in At-Risk Older Adults: Follow-up From the LIFE Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2018Trial
- Multicomponent physical exercise with simultaneous cognitive training to enhance dual-task walking of older adults: a secondary analysis of a 6-month randomized controlled trial with 1-year follow-up.Clinical interventions in aging · 2015Trial
- Do ACE inhibitors improve the response to exercise training in functionally impaired older adults? A randomized controlled trial.The journals of gerontology. Series A, Biological sciences and medical sciences · 2014Trial
- Effect of repeated hot water immersion on muscle strength, power, function and physical activity in healthy older adults: A randomised crossover trial.Experimental physiology · 2026Article
- Effects of a Personalized Augmented Reality Exercise Program Based on Basic Fitness on Key Components of Physical Fitness in Healthy Adults: A Randomized Controlled Trial.Bioengineering (Basel, Switzerland) · 2025Article
- Enhancing physical fitness in older adults: a six-month medium intensity training intervention yields significant improvements.BMC sports science, medicine & rehabilitation · 2025Article
- Short- and Long-Term Effects on Physical Fitness in Older Adults: Results from an 8-Week Exercise Program Repeated in Two Consecutive Years.Geriatrics (Basel, Switzerland) · 2025Article
- Hybrid model of care for older persons for improvement of frailty index-a community-based interventional study in an urban setting.BMC geriatrics · 2024Article
- Prior Engagement in Physical Activity Correlates with Enhanced Quality of Life Perceptions among Older Adults during COVID-19 Lockdown.Brain sciences · 2024Article
- The Relationship between Modified Short Physical Performance Battery and Falls: A Cross-Sectional Study of Older Outpatients.Geriatrics (Basel, Switzerland) · 2021Article
- Association of Health Literacy with the Implementation of Exercise during the Declaration of COVID-19 State of Emergency among Japanese Community-Dwelling Old-Old Adults.International journal of environmental research and public health · 2021Article
- Implementing Precision Medicine in Human Frailty through Epigenetic Biomarkers.International journal of environmental research and public health · 2021Review
- Reversal of age-associated frailty by controlled physical exercise: The pre-clinical and clinical evidences.Sports medicine and health science · 2019Review
- Physical activity, body functions and disability among middle-aged and older Spanish adults.BMC geriatrics · 2017Article
- Objectively measured physical activity and physical performance in old age.Age and ageing · 2017Article
- Effects of inpatient physical therapy on the functional status of elderly individuals.Journal of physical therapy science · 2016Article
- Association of change in brain structure to objectively measured physical activity and sedentary behavior in older adults: Age, Gene/Environment Susceptibility-Reykjavik Study.Behavioural brain research · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOlder adults have the highest rates of disability, functional dependence and use of healthcare resources. Training interventions for older individuals are of special interest where regular physical activity (PA) has many health benefits. The main purpose of this study was to assess the immediate and long-term effects of a 6-month multimodal training intervention (MTI) on functional fitness in old adults.
methodsFor this study, 117 participants, 71 to 90 years old, were randomized in immediate intervention group and a control group (delayed intervention group). The intervention consisted of daily endurance and twice-a-week strength training. The method was based on a randomized-controlled cross-over design. Short Physical Performance Battery (SPPB), 8 foot up-and-go test, strength performance, six min walking test (6 MW), physical activity, BMI and quality of life were obtained at baseline, after a 6-month intervention- and control phase, again after 6-month crossover- and delayed intervention phase, and after anadditional 6-month follow-up.
resultsAfter 6 months of MTI, the intervention group improved in physical performance compared with the control group via Short Physical Performance Battery (SPPB) score (mean diff = 0.6, 95 % CI: 0.1, 1.0) and 8-foot up-and-go test (mean diff = -1.0 s, 95 % CI: -1.5, -0.6), and in endurance performance via 6-minute walking test (6 MW) (mean diff = 44.2 meters, 95 % CI: 17.1, 71.2). In strength performance via knee extension the intervention group improved while control group declined (mean diff = 55.0 Newton, 95 % CI: 28.4, 81.7), and also in PA (mean diff = 125.9 cpm, 95 % CI: 96.0, 155.8). Long-term effects of MTI on the particpants was assesed by estimating the mean difference in the variables measured between time-point 1 and 4: SPPB (1.1 points, 95 % CI: 0.8, 1.4); 8-foot up-and-go (-0.9 s, 95 % CI: -1.2, -0.6); 6 MW (18.7 m, 95 % CI: 6.5, 31.0); knee extension (4.2 Newton, 95 % CI: -10.0, 18.3); hand grip (6.7 Newton, 95 % CI: -4.4, 17.8); PA (-4.0 cpm, 95 % CI: -33.9, 26.0); BMI (-0.6 kg/m2, 95 % CI: -0.9, -0.3) and Icelandic quality of life (0.3 points, 95 % CI: -0.7, 1.4).
conclusionsOur results suggest that regular MTI can improve and prevent decline in functional fitness in older individuals, influence their lifestyle and positively affect their ability to stay independent, thus reducing the need for institutional care.
trial registrationThis study was approved by the National Bioethics Committee in Iceland, VSNb20080300114/03-1.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.