Evidence map›Paper›PMID 22963328›Full record

Trial reportThe international journal of behavioral nutrition and physical activity2012

Effects of a 6-month multimodal training intervention on retention of functional fitness in older adults: a randomized-controlled cross-over design.

Janus Gudlaugsson, Vilmundur Gudnason, Thor Aspelund, Kristin Siggeirsdottir, Anna S Olafsdottir, Palmi V Jonsson, Sigurbjorn A Arngrimsson, Tamara B Harris, Erlingur Johannsson

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The international journal of behavioral nutrition and physical activity, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 72 citations in OpenAlex.

  1. Trial
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  4. Maintenance of Physical Function 1 Year After Exercise Intervention in At-Risk Older Adults: Follow-up From the LIFE Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2018
    Trial
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  6. Do ACE inhibitors improve the response to exercise training in functionally impaired older adults? A randomized controlled trial.The journals of gerontology. Series A, Biological sciences and medical sciences · 2014
    Trial
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  15. Implementing Precision Medicine in Human Frailty through Epigenetic Biomarkers.International journal of environmental research and public health · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Janus GudlaugssonCentre for Research in Sport and Health Sciences, University of Iceland, Laugarvatn, Iceland.
Vilmundur Gudnason
Thor Aspelund
Kristin Siggeirsdottir
Anna S Olafsdottir
Palmi V Jonsson
Sigurbjorn A Arngrimsson
Tamara B Harris
Erlingur Johannsson
University of Iceland · ISIcelandic Heart Association · ISNational Institute on Aging · USNational University Hospital of Iceland · IS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOlder adults have the highest rates of disability, functional dependence and use of healthcare resources. Training interventions for older individuals are of special interest where regular physical activity (PA) has many health benefits. The main purpose of this study was to assess the immediate and long-term effects of a 6-month multimodal training intervention (MTI) on functional fitness in old adults.

methodsFor this study, 117 participants, 71 to 90 years old, were randomized in immediate intervention group and a control group (delayed intervention group). The intervention consisted of daily endurance and twice-a-week strength training. The method was based on a randomized-controlled cross-over design. Short Physical Performance Battery (SPPB), 8 foot up-and-go test, strength performance, six min walking test (6 MW), physical activity, BMI and quality of life were obtained at baseline, after a 6-month intervention- and control phase, again after 6-month crossover- and delayed intervention phase, and after anadditional 6-month follow-up.

resultsAfter 6 months of MTI, the intervention group improved in physical performance compared with the control group via Short Physical Performance Battery (SPPB) score (mean diff = 0.6, 95 % CI: 0.1, 1.0) and 8-foot up-and-go test (mean diff = -1.0 s, 95 % CI: -1.5, -0.6), and in endurance performance via 6-minute walking test (6 MW) (mean diff = 44.2 meters, 95 % CI: 17.1, 71.2). In strength performance via knee extension the intervention group improved while control group declined (mean diff = 55.0 Newton, 95 % CI: 28.4, 81.7), and also in PA (mean diff = 125.9 cpm, 95 % CI: 96.0, 155.8). Long-term effects of MTI on the particpants was assesed by estimating the mean difference in the variables measured between time-point 1 and 4: SPPB (1.1 points, 95 % CI: 0.8, 1.4); 8-foot up-and-go (-0.9 s, 95 % CI: -1.2, -0.6); 6 MW (18.7 m, 95 % CI: 6.5, 31.0); knee extension (4.2 Newton, 95 % CI: -10.0, 18.3); hand grip (6.7 Newton, 95 % CI: -4.4, 17.8); PA (-4.0 cpm, 95 % CI: -33.9, 26.0); BMI (-0.6 kg/m2, 95 % CI: -0.9, -0.3) and Icelandic quality of life (0.3 points, 95 % CI: -0.7, 1.4).

conclusionsOur results suggest that regular MTI can improve and prevent decline in functional fitness in older individuals, influence their lifestyle and positively affect their ability to stay independent, thus reducing the need for institutional care.

trial registrationThis study was approved by the National Bioethics Committee in Iceland, VSNb20080300114/03-1.

Indexed as

Activities of Daily LivingQuality of LifeAgedAged, 80 and overAgingBody Mass IndexCross-Over StudiesFemaleGeriatric AssessmentHumansMalePhysical EndurancePhysical FitnessResistance TrainingWalking

Identifiers

PMID22963328
PMCPMC3522556
OpenAlexW2147095585

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.