ArticleBMC genomics2012
Metagenomic analysis reveals a functional signature for biomass degradation by cecal microbiota in the leaf-eating flying squirrel (Petaurista alborufus lena).
Article in BMC genomics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 34 citations in OpenAlex.
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- Characterization of BrGH3A, a bovine rumen-derived glycoside hydrolase family 3 β-glucosidase with a permuted domain arrangement.PloS one · 2024Article
- Favorite Parts of a Single Leaf for Giant Flying Squirrels to Eat in Three Species of Food Trees.Biology · 2023Article
- Comparison of the Gut Microbial Communities of Domestic and Wild Mallards (Animals : an open access journal from MDPI · 2023Article
- Role of metagenomics in prospecting novel endoglucanases, accentuating functional metagenomics approach in second-generation biofuel production: a review.Biomass conversion and biorefinery · 2023Review
- Comparative Analysis of the Fecal Microbiota of Relict Gull (Frontiers in veterinary science · 2022Article
- Comparative analysis of intestinal flora between rare wild red-crowned crane and white-naped crane.Frontiers in microbiology · 2022Article
- Comparative Analysis of the Fecal Bacterial Microbiota of Wintering Whooper Swans (Frontiers in veterinary science · 2021Article
- Comparative Analysis of the Gut Microbial Communities of the Eurasian Kestrel (Frontiers in microbiology · 2020Article
- Metagenomic analysis of captive Amur tiger faecal microbiome.BMC veterinary research · 2018Article
- Seasonal changes in leaf chemistry and leaf selection of the Japanese giant flying squirrel upon two tree species.Ecology and evolution · 2017Article
- Functional Characteristics of the Flying Squirrel's Cecal Microbiota under a Leaf-Based Diet, Based on Multiple Meta-Omic Profiling.Frontiers in microbiology · 2017Article
- Article
- Spatial heterogeneity of gut microbiota reveals multiple bacterial communities with distinct characteristics.Scientific reports · 2014Article
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAnimals co-evolve with their gut microbiota; the latter can perform complex metabolic reactions that cannot be done independently by the host. Although the importance of gut microbiota has been well demonstrated, there is a paucity of research regarding its role in foliage-foraging mammals with a specialized digestive system.
resultsIn this study, a 16S rRNA gene survey and metagenomic sequencing were used to characterize genetic diversity and functional capability of cecal microbiota of the folivorous flying squirrel (Petaurista alborufus lena). Phylogenetic compositions of the cecal microbiota derived from 3 flying squirrels were dominated by Firmicutes. Based on end-sequences of fosmid clones from 1 flying squirrel, we inferred that microbial metabolism greatly contributed to intestinal functions, including degradation of carbohydrates, metabolism of proteins, and synthesis of vitamins. Moreover, 33 polysaccharide-degrading enzymes and 2 large genomic fragments containing a series of carbohydrate-associated genes were identified.
conclusionsCecal microbiota of the leaf-eating flying squirrel have great metabolic potential for converting diverse plant materials into absorbable nutrients. The present study should serve as the basis for future investigations, using metagenomic approaches to elucidate the intricate mechanisms and interactions between host and gut microbiota of the flying squirrel digestive system, as well as other mammals with similar adaptations.
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