Trial reportThe European journal of health economics : HEPAC : health economics in prevention and care2013
The cost-effectiveness of smoking cessation support delivered by mobile phone text messaging: Txt2stop.
Trial report in The European journal of health economics : HEPAC : health economics in prevention and care, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers, 14 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
92 citing papers in PubMed, 14 syntheses or guidelines pooled it.
- Motivational support intervention to reduce smoking and increase physical activity in smokers not ready to quit: the TARS RCT.Health technology assessment (Winchester, England) · 2023Pooled it
- Digital interventions in mental health: evidence syntheses and economic modelling.Health technology assessment (Winchester, England) · 2022Pooled it
- Smoking Cessation Apps: A Systematic Review of Format, Outcomes, and Features.International journal of environmental research and public health · 2021Pooled it
- Mobile phone-based interventions for improving adherence to medication prescribed for the primary prevention of cardiovascular disease in adults.The Cochrane database of systematic reviews · 2021Pooled it
- Targeted client communication via mobile devices for improving sexual and reproductive health.The Cochrane database of systematic reviews · 2020Pooled it
- Targeted client communication via mobile devices for improving maternal, neonatal, and child health.The Cochrane database of systematic reviews · 2020Pooled it
- Pooled it
- Mobile phone-based interventions for improving adherence to medication prescribed for the primary prevention of cardiovascular disease in adults.The Cochrane database of systematic reviews · 2018Pooled it
- Text Messaging Interventions on Cancer Screening Rates: A Systematic Review.Journal of medical Internet research · 2017Pooled it
- Model-based economic evaluations in smoking cessation and their transferability to new contexts: a systematic review.Addiction (Abingdon, England) · 2017Pooled it
- What is the economic evidence for mHealth? A systematic review of economic evaluations of mHealth solutions.PloS one · 2017Pooled it
- Mobile phone-based interventions for smoking cessation.The Cochrane database of systematic reviews · 2016Pooled it
- Mobile phone-based interventions for improving contraception use.The Cochrane database of systematic reviews · 2015Pooled it
- The effectiveness of mobile-health technology-based health behaviour change or disease management interventions for health care consumers: a systematic review.PLoS medicine · 2013Pooled it
- Impact of Ecological Momentary Assessment Participation on Short-Term Smoking Cessation: quitSTART Ecological Momentary Assessment Incentivization Randomized Trial.Journal of medical Internet research · 2025Trial
- Project phoenix: Pilot randomized controlled trial of a smartphone-delivered intervention for people who are not ready to quit smoking.Drug and alcohol dependence · 2024Trial
- A pilot adaptive trial of text messages, mailed nicotine replacement therapy, and telephone coaching among primary care patients who smoke.Journal of substance use and addiction treatment · 2023Trial
- Effectiveness of a behavioural intervention delivered by text messages (safetxt) on sexually transmitted reinfections in people aged 16-24 years: randomised controlled trial.BMJ (Clinical research ed.) · 2022Trial
- Mobile-health intervention for smoking cessation among Cambodian people living with HIV: A mixed-methods pilot study.AIDS care · 2022Trial
- Adaptation and Assessment of a Text Messaging Smoking Cessation Intervention in Vietnam: Pilot Randomized Controlled Trial.JMIR mHealth and uHealth · 2021Trial
32 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
backgroundThe txt2stop trial has shown that mobile-phone-based smoking cessation support doubles biochemically validated quitting at 6 months. This study examines the cost-effectiveness of smoking cessation support delivered by mobile phone text messaging.
methodsThe lifetime incremental costs and benefits of adding text-based support to current practice are estimated from a UK NHS perspective using a Markov model. The cost-effectiveness was measured in terms of cost per quitter, cost per life year gained and cost per QALY gained. As in previous studies, smokers are assumed to face a higher risk of experiencing the following five diseases: lung cancer, stroke, myocardial infarction, chronic obstructive pulmonary disease, and coronary heart disease (i.e. the main fatal or disabling, but by no means the only, adverse effects of prolonged smoking). The treatment costs and health state values associated with these diseases were identified from the literature. The analysis was based on the age and gender distribution observed in the txt2stop trial. Effectiveness and cost parameters were varied in deterministic sensitivity analyses, and a probabilistic sensitivity analysis was also performed.
findingsThe cost of text-based support per 1,000 enrolled smokers is £16,120, which, given an estimated 58 additional quitters at 6 months, equates to £278 per quitter. However, when the future NHS costs saved (as a result of reduced smoking) are included, text-based support would be cost saving. It is estimated that 18 LYs are gained per 1,000 smokers (0.3 LYs per quitter) receiving text-based support, and 29 QALYs are gained (0.5 QALYs per quitter). The deterministic sensitivity analysis indicated that changes in individual model parameters did not alter the conclusion that this is a cost-effective intervention. Similarly, the probabilistic sensitivity analysis indicated a >90 % chance that the intervention will be cost saving.
interpretationThis study shows that under a wide variety of conditions, personalised smoking cessation advice and support by mobile phone message is both beneficial for health and cost saving to a health system.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.