ArticlePlant physiology2012
Impaired auxin biosynthesis in the defective endosperm18 mutant is due to mutational loss of expression in the ZmYuc1 gene encoding endosperm-specific YUCCA1 protein in maize.
Article in Plant physiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers.
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Who cites it
80 citing papers in PubMed, 156 citations in OpenAlex.
- Molecular understanding of plant pollination, fertilization, seed development and protoplast regeneration.Science China. Life sciences · 2026Review
- EMF2b-1 regulates endosperm cell cycling through PRC2 recruitment in maize.Genome biology · 2026Article
- ZmMYB127 Modulates Maize Kernel Texture and Size by Integrating the Synthesis of Starch, Zein Proteins and Auxin.Plant biotechnology journal · 2026Article
- Unraveling the genetic basis of maize ear diameter in a multi-parent RIL population derived from tropical and temperate germplasms.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- The triggering mechanism for predominant hormonal signal production in fleshy fruit ripening.Molecular horticulture · 2025Review
- The aleurone layer of cereal grains: Development, genetic regulation, and breeding applications.Plant communications · 2025Review
- Genome wide identification of Dof transcription factors in Carmine radish reveals RsDof33 role in cadmium stress and anthocyanin biosynthesis.Scientific reports · 2025Article
- Hormonal regulation and crosstalk during early endosperm and seed coat development.Plant reproduction · 2024Review
- ZmICE1a regulates the defence-storage trade-off in maize endosperm.Nature plants · 2024Article
- Molecular mechanisms controlling grain size and weight and their biotechnological breeding applications in maize and other cereal crops.Journal of advanced research · 2024Review
- Article
- An ARF gene mutation creates flint kernel architecture in dent maize.Nature communications · 2024Article
- The conservation of allelic DNA methylation and its relationship with imprinting in maize.Journal of experimental botany · 2024Article
- QTL Detection and Candidate Gene Identification for Eating and Cooking Quality Traits in Rice (International journal of molecular sciences · 2024Article
- Phenotypic characterization and candidate gene analysis of a short kernel and brassinosteroid insensitive mutant from hexaploid oat (Frontiers in plant science · 2024Article
- Unveiling the imprinted dance: how parental genomes orchestrate seed development and hybrid success.Frontiers in plant science · 2024Review
- Genetic architecture of kernel-related traits in sweet and waxy maize revealed by genome-wide association analysis.Frontiers in genetics · 2024Article
- Multi-locus genome-wide association study for phosphorus use efficiency in a tropical maize germplasm.Frontiers in plant science · 2024Article
- MaizeInternational journal of molecular sciences · 2023Article
- Roles of auxin pathways in maize biology.Journal of experimental botany · 2023Review
20 more citing papers are in PubMed but not listed here.
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Authors and funding
9 authors at 6 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The phytohormone auxin (indole-3-acetic acid [IAA]) plays a fundamental role in vegetative and reproductive plant development. Here, we characterized a seed-specific viable maize (Zea mays) mutant, defective endosperm18 (de18) that is impaired in IAA biosynthesis. de18 endosperm showed large reductions of free IAA levels and is known to have approximately 40% less dry mass, compared with De18. Cellular analyses showed lower total cell number, smaller cell volume, and reduced level of endoreduplication in the mutant endosperm. Gene expression analyses of seed-specific tryptophan-dependent IAA pathway genes, maize Yucca1 (ZmYuc1), and two tryptophan-aminotransferase co-orthologs were performed to understand the molecular basis of the IAA deficiency in the mutant. Temporally, all three genes showed high expression coincident with high IAA levels; however, only ZmYuc1 correlated with the reduced IAA levels in the mutant throughout endosperm development. Furthermore, sequence analyses of ZmYuc1 complementary DNA and genomic clones revealed many changes specific to the mutant, including a 2-bp insertion that generated a premature stop codon and a truncated YUC1 protein of 212 amino acids, compared with the 400 amino acids in the De18. The putative, approximately 1.5-kb, Yuc1 promoter region also showed many rearrangements, including a 151-bp deletion in the mutant. Our concurrent high-density mapping and annotation studies of chromosome 10, contig 395, showed that the De18 locus was tightly linked to the gene ZmYuc1. Collectively, the data suggest that the molecular changes in the ZmYuc1 gene encoding the YUC1 protein are the causal basis of impairment in a critical step in IAA biosynthesis, essential for normal endosperm development in maize.
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