ArticleThe Plant cell2012
Overexpression of Arabidopsis plasmodesmata germin-like proteins disrupts root growth and development.
Article in The Plant cell, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 1 synthesis or guideline pooled it, 90 citations in OpenAlex.
- A comparative meta-proteomic pipeline for the identification of plasmodesmata proteins and regulatory conditions in diverse plant species.BMC biology · 2022Pooled it
- SMXL3 controls multiple aspects of Arabidopsis development via EAR motif-dependent and -independent functions.The Plant journal : for cell and molecular biology · 2026Article
- Genome-Wide Identification and Salinity Response Analysis of the Germin-like Protein (Plants (Basel, Switzerland) · 2025Article
- Loss-of-Function of Two PD-Associated Proteins Confers Resistance to Rice Stripe Virus.Molecular plant pathology · 2025Article
- GERMIN3 regulates tuber initiation and axillary bud activation by facilitating plasmodesmatal gating.The Plant journal : for cell and molecular biology · 2025Article
- Novel resources to investigate leaf plasmodesmata formation in CThe Plant journal : for cell and molecular biology · 2024Article
- Roles of Germin-like Protein Family in Response to Seed Germination and Shoot Branching inInternational journal of molecular sciences · 2024Article
- Evolutionary and Structural Analysis of PP16 in Viridiplantae.International journal of molecular sciences · 2024Article
- Phloem-MobilePlants (Basel, Switzerland) · 2023Article
- Plasmodesmal endoplasmic reticulum proteins regulate intercellular trafficking of cucumber mosaic virus in Arabidopsis.Journal of experimental botany · 2023Article
- Molecular mechanisms underpinning quantitative resistance toFrontiers in plant science · 2023Article
- Analysis of plasmodesmata permeability using cultured tobacco BY-2 cells entrapped in microfluidic chips.Journal of plant research · 2022Article
- Genome-Wide Identification, Characterization, and Expression Analysis Related to Low-Temperature Stress of theInternational journal of molecular sciences · 2022Article
- Accelerated remodeling of the mesophyll-bundle sheath interface in the maize C4 cycle mutant leaves.Scientific reports · 2022Article
- Germin like protein genes exhibit modular expression during salt and drought stress in elite rice cultivars.Molecular biology reports · 2022Article
- Transcriptome and Small RNA Sequencing Reveal the Mechanisms Regulating Harvest Index inFrontiers in plant science · 2022Article
- Article
- Plasmodesmata Structural Components and Their Role in Signaling and Plant Development.Methods in molecular biology (Clifton, N.J.) · 2022Review
- Subtilase activity in intrusive cells mediates haustorium maturation in parasitic plants.Plant physiology · 2021Article
- TERMINAL FLOWER-1/CENTRORADIALIS inhibits tuberisation via protein interaction with the tuberigen activation complex.The Plant journal : for cell and molecular biology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In plants, a population of non-cell-autonomous proteins (NCAPs), including numerous transcription factors, move cell to cell through plasmodesmata (PD). In many cases, the intercellular trafficking of these NCAPs is regulated by their interaction with specific PD components. To gain further insight into the functions of this NCAP pathway, coimmunoprecipitation experiments were performed on a tobacco (Nicotiana tabacum) plasmodesmal-enriched cell wall protein preparation using as bait the NCAP, pumpkin (Cucurbita maxima) PHLOEM PROTEIN16 (Cm-PP16). A Cm-PP16 interaction partner, Nt-PLASMODESMAL GERMIN-LIKE PROTEIN1 (Nt-PDGLP1) was identified and shown to be a PD-located component. Arabidopsis thaliana putative orthologs, PDGLP1 and PDGLP2, were identified; expression studies indicated that, postgermination, these proteins were preferentially expressed in the root system. The PDGLP1 signal peptide was shown to function in localization to the PD by a novel mechanism involving the endoplasmic reticulum-Golgi secretory pathway. Overexpression of various tagged versions altered root meristem function, leading to reduced primary root but enhanced lateral root growth. This effect on root growth was corrected with an inability of these chimeric proteins to form stable PD-localized complexes. PDGLP1 and PDGLP2 appear to be involved in regulating primary root growth by controlling phloem-mediated allocation of resources between the primary and lateral root meristems.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.