Evidence map›Paper›PMID 22960632›Full record

ArticleThe EMBO journal2012

RING-between-RINGs--keeping the safety on loaded guns.

Katja K Dove, Rachel E Klevit

Abstract readComment
In one paragraph

Article in The EMBO journal, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. E2 variants for probing E3 ubiquitin ligase activities.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Review
  3. Targeted protein degradation: elements of PROTAC design.Current opinion in chemical biology · 2019
    Review
  4. HIF and HOIL-1L-mediated PKCζ degradation stabilizes plasma membrane Na,K-ATPase to protect against hypoxia-induced lung injury.Proceedings of the National Academy of Sciences of the United States of America · 2017
    Article
  5. Role of Linear Ubiquitination in Health and Disease.American journal of respiratory cell and molecular biology · 2016
    Review
  6. Role of ubiquitin and the HPV E6 oncoprotein in E6AP-mediated ubiquitination.Proceedings of the National Academy of Sciences of the United States of America · 2015
    Article
  7. HOIL-1L functions as the PKCζ ubiquitin ligase to promote lung tumor growth.American journal of respiratory and critical care medicine · 2014
    Article
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Katja K DoveDepartment of Biochemistry, University of Washington, Seattle, WA, USA.
Rachel E Klevit

Funding

Structural and Functional Characterization of BRCA1/BARD1R01GM088055 · NIGMS · UNIVERSITY OF WASHINGTON · PI KLEVIT, RACHEL E · 2009 to 2020
$6.5M
NIGMS NIH HHS R01 GM088055
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Carrier ProteinsHumansUbiquitinUbiquitin-Protein LigasesCarrier ProteinsRNF31 protein, humanUbiquitinUbiquitin-Protein Ligases

Identifiers

PMID22960632
PMCPMC3463855

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.