Evidence map›Paper›PMID 22960604›Full record

ReviewCellular & molecular immunology2012

Germinal center kinases in immune regulation.

Hailei Yin, Zhubing Shi, Shi Jiao, Cuicui Chen, Wenjia Wang, Mark I Greene, Zhaocai Zhou

Abstract readReview
In one paragraph

Review in Cellular & molecular immunology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Study of Expression ofMedical sciences (Basel, Switzerland) · 2025
    Article
  2. TNIK in disease: from molecular insights to therapeutic prospects.Apoptosis : an international journal on programmed cell death · 2024
    Review
  3. Article
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  16. Mitochondria in the center of human eosinophil apoptosis and survival.International journal of molecular sciences · 2014
    Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hailei YinDepartment of Trauma and Orthopaedics, General Hospital of Jinan Military Region, Jinan, China.
Zhubing Shi
Shi Jiao
Cuicui Chen
Wenjia Wang
Mark I Greene
Zhaocai Zhou

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Germinal center kinases (GCKs) participate in a variety of signaling pathways needed to regulate cellular functions including apoptosis, cell proliferation, polarity and migration. Recent studies have shown that GCKs are participants in both adaptive and innate immune regulation. However, the differential activation and regulatory mechanisms of GCKs, as well as upstream and downstream signaling molecules, remain to be fully defined. It remains unresolved whether and how GCKs may cross-talk with existing signaling pathways. This review stresses the progresses in research of GCKs relevant to the immune system.

Indexed as

AnimalsGerminal Center KinasesHumansImmunityInflammationLymphocytesModels, ImmunologicalProtein Serine-Threonine KinasesSignal TransductionGerminal Center KinasesProtein Serine-Threonine Kinases

Identifiers

PMID22960604
PMCPMC4002213

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.