Evidence map›Paper›PMID 22959616›Full record

ArticleAccident; analysis and prevention2013

Classifying performance impairment in response to sleep loss using pattern recognition algorithms on single session testing.

Melissa A St Hilaire, Jason P Sullivan, Clare Anderson, Daniel A Cohen, Laura K Barger, Steven W Lockley, Elizabeth B Klerman

Abstract read
In one paragraph

Article in Accident; analysis and prevention, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Melissa A St HilaireAnalytic and Modeling Unit, Division of Sleep Medicine, Brigham and Women's Hospital, 221 Longwood Avenue, Boston, MA 02115, USA. msthilaire@rics.bwh.harvard.edu
Jason P Sullivan
Clare Anderson
Daniel A Cohen
Laura K Barger
Steven W Lockley
Elizabeth B Klerman

Funding

HARVARD CLINICAL AND TRANSLATIONAL SCIENCE CENTER (UL1)UL1RR025758 · NCRR · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2008 to 2011
$91.4M
Zoledronic Acid in Treatment of Osteoporosis in PostmenoM01RR002635 · NCRR · BRIGHAM AND WOMEN'S HOSPITAL · PI WELT, CORRINE K · 1985 to 2008
$48.4M
TRANSPLANTATION ANALYSIS OF CIRCADIAN RHYTHMS AND AGINGP01AG009975 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI CZEISLER, CHARLES A · 1991 to 2018
$23.1M
TRAINING IN SLEEP, CIRCADIAN &RESPIRATORY NEUROBIOLOGYT32HL007901 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI Charles A Czeisler · 1998 to 2026
$18.5M
Sleep duration required to restore performance during chronic sleep restrictionR01HL114088 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI KLERMAN, ELIZABETH B. · 2012 to 2015
$3.1M
Sleep Duration Required to Restore Performance during Chronic Sleep RestrictionK24HL105664 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI KLERMAN, ELIZABETH B. · 2010 to 2019
$1.8M
Human circadian sensitivity to very short light pulsesRC2HL101340 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI KLERMAN, ELIZABETH B. · 2009 to 2010
$1.3M
INTEGRATIVE GENOMICS APPROACHES TO MODEL THE GENETIC ARCHITECTURE OF ASTHMAR00HL105663 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI HIMES, BLANCA E · 2013 to 2015
$702k
Impact of Sleep Disruption on Menstrual Cycle DynamicsK02HD045459 · NICHD · BRIGHAM AND WOMEN'S HOSPITAL · PI KLERMAN, ELIZABETH B. · 2004 to 2008
$543k
INTEGRATIVE GENOMICS APPROACHES TO MODEL THE GENETIC ARCHITECTURE OF ASTHMAK99HL105663 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI HIMES, BLANCA E · 2011 to 2012
$275k
Effects of Extended Work Hours on Intern Health &SafetyR01OH007567 · OH · BRIGHAM AND WOMEN'S HOSPITAL · PI CZEISLER, CHARLES A · 2001 to 2004
–
Effects of Extended Work Hours on ICU Patient SafetyR01HS012032 · AHRQ · BRIGHAM AND WOMEN'S HOSPITAL · PI CZEISLER, CHARLES A · 2001 to 2003
–
AHRQ HHS R01 HS012032AHRQ HHS R01 HS12032NCRR NIH HHS 1 UL1 RR025758NCRR NIH HHS M01 RR002635NCRR NIH HHS M01 RR02635NCRR NIH HHS UL1 RR025758NHLBI NIH HHS K24-HL105663NHLBI NIH HHS K24 HL105664NHLBI NIH HHS K99 HL105663NHLBI NIH HHS R00 HL105663NHLBI NIH HHS R01 HL114088NHLBI NIH HHS RC2 HL101340NHLBI NIH HHS RC2-HL101340NHLBI NIH HHS RC2-HL101340-0NHLBI NIH HHS T32 HL007901NHLBI NIH HHS T32-HL07901NIA NIH HHS P01 AG009975NIA NIH HHS P01-AG009975NICHD NIH HHS K02 HD045459NICHD NIH HHS K02-HD045459NIOSH CDC HHS R01 OH007567NIOSH CDC HHS R01 OH07567
6 · The paper itself

Abstract

There is currently no "gold standard" marker of cognitive performance impairment resulting from sleep loss. We utilized pattern recognition algorithms to determine which features of data collected under controlled laboratory conditions could most reliably identify cognitive performance impairment in response to sleep loss using data from only one testing session, such as would occur in the "real world" or field conditions. A training set for testing the pattern recognition algorithms was developed using objective Psychomotor Vigilance Task (PVT) and subjective Karolinska Sleepiness Scale (KSS) data collected from laboratory studies during which subjects were sleep deprived for 26-52h. The algorithm was then tested in data from both laboratory and field experiments. The pattern recognition algorithm was able to identify performance impairment with a single testing session in individuals studied under laboratory conditions using PVT, KSS, length of time awake and time of day information with sensitivity and specificity as high as 82%. When this algorithm was tested on data collected under real-world conditions from individuals whose data were not in the training set, accuracy of predictions for individuals categorized with low performance impairment were as high as 98%. Predictions for medium and severe performance impairment were less accurate. We conclude that pattern recognition algorithms may be a promising method for identifying performance impairment in individuals using only current information about the individual's behavior. Single testing features (e.g., number of PVT lapses) with high correlation with performance impairment in the laboratory setting may not be the best indicators of performance impairment under real-world conditions. Pattern recognition algorithms should be further tested for their ability to be used in conjunction with other assessments of sleepiness in real-world conditions to quantify performance impairment in response to sleep loss.

Indexed as

AlgorithmsPattern Recognition, AutomatedSleep DeprivationAdolescentAdultAgedArousalAttentionFemaleHumansMaleMiddle AgedPredictive Value of TestsPsychomotor PerformanceReaction TimeSensitivity and Specificity

Identifiers

PMID22959616
PMCPMC3513628

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.