Evidence map›Paper›PMID 22959032›Full record

ReviewAdvances in pharmacology (San Diego, Calif.)2012

Chemoprevention of melanoma.

Subbarao V Madhunapantula, Gavin P Robertson

Abstract readReview
In one paragraph

Review in Advances in pharmacology (San Diego, Calif.), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Rhabdoid melanoma in a harpy eagle (Veterinary and animal science · 2021
    Article
  3. Use of Nanoparticles in Delivery of Nucleic Acids for Melanoma Treatment.Methods in molecular biology (Clifton, N.J.) · 2021
    Article
  4. Characterization ofAntioxidants (Basel, Switzerland) · 2020
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. MIR-520f Regulated Itch Expression and Promoted Cell Proliferation in Human Melanoma Cells.Dose-response : a publication of International Hormesis Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Subbarao V MadhunapantulaJagadguru Sri Shivarathreeshwara Medical College, Jagadguru Sri Shivarathreeshwara University, Mysore, Karnataka, India.
Gavin P Robertson

Funding

Akt3 Signaling as a Therapeutic TargetR01CA127892 · NCI · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI ROBERTSON, GAVIN P. · 2008 to 2012
$1.5M
NCI NIH HHS CA-127892-01ANCI NIH HHS R01 CA127892
6 · The paper itself

Abstract

Despite advances in drug discovery programs and molecular approaches for identifying drug targets, incidence and mortality rates due to melanoma continue to rise at an alarming rate. Existing preventive strategies generally involve mole screening followed by surgical removal of the benign nevi and abnormal moles. However, due to lack of effective programs for screening and disease recurrence after surgical resection, there is a need for better chemopreventive agents. Although sunscreens have been used extensively for protecting from UV-induced melanomas, results of correlative population-based studies are controversial, with certain studies suggest increased skin cancer risk in sunscreen users. Therefore, these studies require further authentication to conclusively confirm the chemoprotective efficacy of sunscreens. This chapter reviews the current understanding regarding melanoma chemoprevention and the various strategies used to accomplish this objective.

Indexed as

ChemopreventionAnimalsAntineoplastic AgentsDisease Models, AnimalHumansMelanomaModels, BiologicalAntineoplastic Agents

Identifiers

PMID22959032
PMCPMC3628531

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.