Evidence map›Paper›PMID 22958872›Full record

ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2012

Solid-organ transplantation in older adults: current status and future research.

M Abecassis, N D Bridges, C J Clancy, M A Dew, B Eldadah, M J Englesbe, M F Flessner, J C Frank, J Friedewald, J Gill and 28 more

Open access · bronzeAbstract readConference Proceedings
In one paragraph

Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed, 1 pooled it
10.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 1 synthesis or guideline pooled it, 137 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Fixing a Mismatch: The Case for Age-Aligned Kidney Allocation.Transplant international : official journal of the European Society for Organ Transplantation · 2025
    Article
  9. Article
  10. Review
  11. Does Age Influence Immunosuppressant Drug Pharmacokinetics in Kidney Transplant Recipients?European journal of drug metabolism and pharmacokinetics · 2024
    Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. The Future of Transplantation.The New England journal of medicine · 2022
    Article
  19. Article
  20. Observational

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

38 authors at 20 institutions in 3 countries.

M AbecassisDepartments of Surgery and Microbiology-Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
N D Bridges
C J Clancy
M A Dew
B Eldadah
M J Englesbe
M F Flessner
J C Frank
J Friedewald
J Gill
C Gries
J B Halter
E L Hartmann
W R Hazzard
F M Horne
J Hosenpud
P Jacobson
B L Kasiske
J Lake
R Loomba
P N Malani
T M Moore
A Murray
M-H Nguyen
N R Powe
P P Reese
H Reynolds
M D Samaniego
K E Schmader
D L Segev
A S Shah
L G Singer
J A Sosa
Z A Stewart
J C Tan
W W Williams
D W Zaas
K P High
National Institutes of Health · USUniversity of Michigan · USUniversity of Pittsburgh · USDuke University · USNorthwestern University · USCalifornia University of Pennsylvania · USHarvard University Press · USJacksonville College · USJohns Hopkins University · USNHS Blood and Transplant · GBStanford University · USTwin Cities Orthopedics · USUniversity of British Columbia · CAUniversity of California, Los Angeles · USUniversity of California San Diego · USUniversity of California, San Francisco · USUniversity of Iowa · USUniversity of Minnesota · USUniversity of Toronto · CAUniversity of Washington · US

Funding

Wake Forest Claude D. Pepper OAIC - RenewalP30AG021332 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Jamie Nicole Justice · 2002 to 2026
$36.4M
Resource Core 3 - Metabolomics CoreP30AG028716 · NIA · DUKE UNIVERSITY · PI Virginia B Kraus · 2006 to 2026
$24.6M
Renal senescence in kidney donorsK23DK087937 · NIDDK · STANFORD UNIVERSITY · PI TAN, JANE C · 2010 to 2014
$892k
A Transdisciplinary Approach to Engage Specialty Investigators in Aging ResearchU13AG040938 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI HIGH, KEVIN P., KRITCHEVSKY, STEPHEN B. · 2011 to 2019
$423k
NIA NIH HHS 1 U13 AG040938-01NIA NIH HHS P30 AG021332NIA NIH HHS P30 AG028716NIA NIH HHS U13 AG040938NIDDK NIH HHS K23 DK087937
6 · The paper itself

Abstract

An increasing number of patients older than 65 years are referred for and have access to organ transplantation, and an increasing number of older adults are donating organs. Although short-term outcomes are similar in older versus younger transplant recipients, older donor or recipient age is associated with inferior long-term outcomes. However, age is often a proxy for other factors that might predict poor outcomes more strongly and better identify patients at risk for adverse events. Approaches to transplantation in older adults vary across programs, but despite recent gains in access and the increased use of marginal organs, older patients remain less likely than other groups to receive a transplant, and those who do are highly selected. Moreover, few studies have addressed geriatric issues in transplant patient selection or management, or the implications on health span and disability when patients age to late life with a transplanted organ. This paper summarizes a recent trans-disciplinary workshop held by ASP, in collaboration with NHLBI, NIA, NIAID, NIDDK and AGS, to address issues related to kidney, liver, lung, or heart transplantation in older adults and to propose a research agenda in these areas.

Indexed as

Organ TransplantationAgedHealth Care RationingHumansImmunosuppressive AgentsPatient SelectionSocial JusticeTissue DonorsTreatment OutcomeImmunosuppressive Agents

Identifiers

PMID22958872
PMCPMC3459231
OpenAlexW1501724616

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.