ArticleNutrition journal2012
Serum 25(OH)D is inversely associated with metabolic syndrome risk profile among urban middle-aged Chinese population.
Article in Nutrition journal, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.
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Who cites it
28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 64 citations in OpenAlex.
- Vitamin D Deficiency Is Inversely Associated with Homeostatic Model Assessment of Insulin Resistance.Nutrients · 2021Pooled it
- Insulin Resistance Is Inversely Associated with the Status of Vitamin D in Both Diabetic and Non-Diabetic Populations.Nutrients · 2021Pooled it
- Trial
- The relationship between vitamin D and insulin resistance before delivery in advanced maternal age.Reproductive biology and endocrinology : RB&E · 2019Trial
- Relationship between Circulating 25-Hydroxyvitamin D and Metabolic Syndrome in Chinese Adults: A Large Nationwide Longitudinal Study.Nutrients · 2024Article
- Vitamin D insufficiency is associated with inflammation and deregulation of adipokines in patients with metabolic syndrome.BMC endocrine disorders · 2022Article
- 25-hydroxyvitamin D levels are inversely related to metabolic syndrome risk profile in northern Chinese subjects without vitamin D supplementation.Diabetology & metabolic syndrome · 2022Article
- Sex-Specific Association between Serum 25-Hydroxyvitamin D and Metabolic Risk Factors in T2DM Patients.International journal of endocrinology · 2020Article
- Vitamin D Status and Correlation with Glucose and Lipid Metabolism in Gansu Province, China.Diabetes, metabolic syndrome and obesity : targets and therapy · 2020Article
- Sleep duration is associated with vitamin D deficiency in older women living in Macao, China: A pilot cross-sectional study.PloS one · 2020Article
- The association of VDR polymorphisms and type 2 diabetes in older people living in community in Santiago de Chile.Nutrition & diabetes · 2018Article
- Dynamic development of metabolic syndrome and its risk prediction in Chinese population: a longitudinal study using Markov model.Diabetology & metabolic syndrome · 2018Article
- The association of vitamin D status and dietary calcium intake with individual components of the metabolic syndrome: a population-based study in Victoria, Australia.Cardiovascular endocrinology · 2017Article
- Article
- Vitamin D deficiency and depression among women from an urban community in a tropical country.Public health nutrition · 2017Article
- Effect of waist circumference on the association between serum 25-hydroxyvitamin D and serum lipids: results from the National Health and Nutrition Examination Survey 2001-2006.Public health nutrition · 2017Article
- The Associations Between Helicobacter pylori Infection, Serum Vitamin D, and Metabolic Syndrome: A Community-Based Study.Medicine · 2016Article
- Vitamin D Status and Cardio-Metabolic Risk in Indian Postmenopausal Women.Journal of clinical and diagnostic research : JCDR · 2016Article
- Article
- The Associations of Serum Lipids with Vitamin D Status.PloS one · 2016Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVitamin D deficiency is associated with a variety of chronic metabolic diseases. Limited evidence regarding vitamin D deficiency exists within the Chinese population. The present study aims to examine the association between serum vitamin D concentrations and cardiometabolic risk factors in the young and middle-aged, urban Chinese population
methodsThe cross-sectional relationships between serum 25-hydroxyvitamin D [25(OH)D] concentrations and indices of adiposity and cardiometabolic risk factors (e.g., body mass index, waist circumference, fasting plasma glucose, etc.) were evaluated in 601 non-diabetic adults.
resultVitamin D deficiency or insufficiency was present in 66% of the tested population, and serum 25(OH)D levels were lower in patients who were overweight/obese or suffered metabolic syndrome when compared to individuals of healthy weight without metabolic syndrome (24.08 ± 8.08 vs 31.70 ± 11.77 ng/ml, 21.52 ± 6.9 vs 31.74 ± 10.21 ng/ml respectively). 25(OH)D was inversely associated with waist circumference, fasting glucose, fasting insulin, triglycerides and LDL-cholesterol, and it was positively associated with HDL-cholesterol in a multivariable-adjusted regression model.
conclusionVitamin D deficiency is common in the young and middle-aged, urban Chinese population, with high prevalence in overweight/obese individuals and patients with metabolic syndrome. Low vitamin D concentration was associated with indices of adiposity and cardiometabolic risk factors. Further studies are warranted to elucidate the cause-effect relation between vitamin D status, obesity and related metabolic disorders.
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