Evidence map›Paper›PMID 22958575›Full record

Trial reportTwin research and human genetics : the official journal of the International Society for Twin Studies2012

Offspring ADHD as a risk factor for parental marital problems: controls for genetic and environmental confounds.

Alice C Schermerhorn, Brian M D'Onofrio, Wendy S Slutske, Robert E Emery, Eric Turkheimer, K Paige Harden, Andrew C Heath, Nicholas G Martin

Open access · bronzeAbstract readClinical TrialMulticenter StudyTwin Study
In one paragraph

Trial report in Twin research and human genetics : the official journal of the International Society for Twin Studies, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Review
  3. The Impact of ADHD on Maternal Quality of Life.Research on child and adolescent psychopathology · 2022
    Article
  4. Article
  5. Article
  6. Article
  7. ADHD and risk for subsequent adverse childhood experiences: understanding the cycle of adversity.Journal of child psychology and psychiatry, and allied disciplines · 2021
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Quality of life, psychological characteristics, and adjustment in parents of children with Attention-Deficit/Hyperactivity Disorder.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2017
    Article
  13. Review
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 2 countries.

Alice C SchermerhornDepartment of Psychological and Brain Sciences, Indiana University, Bloomington, IN, USA.
Brian M D'Onofrio
Wendy S Slutske
Robert E Emery
Eric Turkheimer
K Paige Harden
Andrew C Heath
Nicholas G Martin
Indiana University Bloomington · USUniversity of Virginia · USQIMR Berghofer Medical Research Institute · AUThe University of Texas at Austin · USUniversity of Missouri · USWashington University in St. Louis · US

Funding

TRAINING PROGRAM IN INTEGRATIVE DEVELOPMENTAL PROCESST32HD007475 · NICHD · TRUSTEES OF INDIANA UNIVERSITY · PI Daniel Patrick Kennedy, LINDA B. SMITH · 1995 to 2026
$9.5M
Twin Studies of the Marriage Benefit: Parsing Selection from CausationR01HD056354 · NICHD · UNIVERSITY OF VIRGINIA · PI EMERY, ROBERT E · 2007 to 2013
$2.3M
GENE-ENVIRONMENT INTERPLAY IN ALCOHOLISMK05AA017688 · NIAAA · WASHINGTON UNIVERSITY · PI HEATH, ANDREW C. · 2008 to 2017
$1.9M
Quasi-experimental studies of early risk factors for severe psychopathologyR01HD061817 · NICHD · TRUSTEES OF INDIANA UNIVERSITY · PI D'ONOFRIO, BRIAN M, LICHTENSTEIN, PAUL · 2010 to 2013
$1.3M
Combinations of genetic and environmental risk for externalization in adolescenceR01HD053550 · NICHD · UNIVERSITY OF VIRGINIA · PI TURKHEIMER, ERIC NATHAN · 2007 to 2010
$928k
Child Temperament and Adaptation to Interparental ConflictR00HD064795 · NICHD · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI SCHERMERHORN, ALICE C · 2012 to 2014
$668k
Child Temperament and Adaptation to Interparental ConflictK99HD064795 · NICHD · TRUSTEES OF INDIANA UNIVERSITY · PI SCHERMERHORN, ALICE C · 2011 to 2012
$177k
PERSISTENCE &CHANGE IN DRINKING HABITS: TWIN STUDYR01AA007535 · NIAAA · WASHINGTON UNIVERSITY · PI HEATH, ANDREW C. · 1989 to 1996
–
NIAAA NIH HHS AA000264NIAAA NIH HHS K05 AA017688NIAAA NIH HHS R01 AA007535NICHD NIH HHS HD053550NICHD NIH HHS HD056354NICHD NIH HHS HD064795NICHD NIH HHS K99 HD064795NICHD NIH HHS R00 HD064795NICHD NIH HHS R01 HD053550NICHD NIH HHS R01 HD056354NICHD NIH HHS R01 HD061817NICHD NIH HHS T32 HD007475NICHD NIH HHS T32HD007475
6 · The paper itself

Abstract

backgroundPrevious studies have found that child attention-deficit/hyperactivity disorder (ADHD) is associated with more parental marital problems. However, the reasons for this association are unclear. The association might be due to genetic or environmental confounds that contribute to both marital problems and ADHD.

methodData were drawn from the Australian Twin Registry, including 1,296 individual twins, their spouses, and offspring. We studied adult twins who were discordant for offspring ADHD.Using a discordant twin pairs design, we examined the extent to which genetic and environmental confounds,as well as measured parental and offspring characteristics, explain the ADHD-marital problems association.

resultsOffspring ADHD predicted parental divorce and marital conflict. The associations were also robust when comparing differentially exposed identical twins to control for unmeasured genetic and environmental factors, when controlling for measured maternal and paternal psychopathology,when restricting the sample based on timing of parental divorce and ADHD onset, and when controlling for other forms of offspring psychopathology. Each of these controls rules out alternative explanations for the association.

conclusionThe results of the current study converge with those of prior research in suggesting that factors directly associated with offspring ADHD increase parental marital problems.

Indexed as

DivorceGene-Environment InteractionAdultAgedAttention Deficit Disorder with HyperactivityAustraliaFemaleFollow-Up StudiesHumansMaleMiddle AgedRetrospective Studies

Identifiers

PMID22958575
PMCPMC3678725
OpenAlexW2112685170

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.