ArticleJournal of neurodevelopmental disorders2012
A cross-sectional study of the development of volitional control of spatial attention in children with chromosome 22q11.2 deletion syndrome.
Article in Journal of neurodevelopmental disorders, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Event-related potential (ERP) markers of 22q11.2 deletion syndrome and associated psychosis.Journal of neurodevelopmental disorders · 2023Review
- The Importance of Understanding Individual Differences of Emotion Regulation Abilities in 22q11.2 Deletion Syndrome.Journal of autism and developmental disorders · 2022Article
- Quantifying the resolution of spatial and temporal representation in children with 22q11.2 deletion syndrome.Journal of neurodevelopmental disorders · 2019Article
- Seeing Eye to Eye With Threat: Atypical Threat Bias in Children With 22q11.2 Deletion Syndrome.American journal on intellectual and developmental disabilities · 2019Article
- Visual processing deficits in 22q11.2 Deletion Syndrome.NeuroImage. Clinical · 2018Article
- Working Memory Impairments in Chromosome 22q11.2 Deletion Syndrome: The Roles of Anxiety and Stress Physiology.Journal of autism and developmental disorders · 2017Article
- The hippocampi of children with chromosome 22q11.2 deletion syndrome have localized anterior alterations that predict severity of anxiety.Journal of psychiatry & neuroscience : JPN · 2016Article
- Behavioral and Psychiatric Phenotypes in 22q11.2 Deletion Syndrome.Journal of developmental and behavioral pediatrics : JDBP · 2015Review
- Common and specific impairments in attention functioning in girls with chromosome 22q11.2 deletion, fragile X or Turner syndromes.Journal of neurodevelopmental disorders · 2014Article
- Children with chromosome 22q11.2 deletion syndrome exhibit impaired spatial working memory.American journal on intellectual and developmental disabilities · 2014Article
- The development of cognitive control in children with chromosome 22q11.2 deletion syndrome.Frontiers in psychology · 2014Article
- A cross-sectional analysis of orienting of visuospatial attention in child and adult carriers of the fragile X premutation.Journal of neurodevelopmental disorders · 2014Article
- A cross-sectional analysis of the development of response inhibition in children with chromosome 22q11.2 deletion syndrome.Frontiers in psychiatry · 2013Article
- 22q11 deletion syndrome: a review of the neuropsychiatric features and their neurobiological basis.Neuropsychiatric disease and treatment · 2013Review
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
backgroundChromosome 22q11.2 deletion syndrome (22q11.2DS) results from a 1.5- to 3-megabase deletion on the long arm of chromosome 22 and occurs in approximately 1 in 4000 live births. Previous studies indicate that children with 22q11.2DS are impaired on tasks involving spatial attention. However, the degree to which these impairments are due to volitionally generated (endogenous) or reflexive (exogenous) orienting of attention is unclear. Additionally, the efficacy of these component attention processes throughout child development in 22q11.2DS has yet to be examined.
methodsHere we compared the performance of a wide age range (7 to 14 years) of children with 22q11.2DS to typically developing (TD) children on a comprehensive visual cueing paradigm to dissociate the contributions of endogenous and exogenous attentional impairments. Paired and two-sample t-tests were used to compare outcome measures within a group or between groups. Additionally, repeated measures regression models were fit to the data in order to examine effects of age on performance.
resultsWe found that children with 22q11.2DS were impaired on a cueing task with an endogenous cue, but not on the same task with an exogenous cue. Additionally, it was younger children exclusively who were impaired on endogenous cueing when compared to age-matched TD children. Older children with 22q11.2DS performed comparably to age-matched TD peers on the endogenous cueing task.
conclusionsThese results suggest that endogenous but not exogenous orienting of attention is selectively impaired in children with 22q11.2DS. Additionally, the age effect on cueing in children with 22q11.2DS suggests a possible altered developmental trajectory of endogenous cueing.
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