ReviewClinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases2012
Deviations in influenza seasonality: odd coincidence or obscure consequence?
Review in Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed.
- The optimal strategy for seasonal influenza vaccination to prevent high-intensity level of influenza epidemics in Zhejiang, China: an integrated transmission-dynamic and health-economic modeling analysis.BMC public health · 2025Article
- Mathematical Modeling of Influenza Dynamics: Integrating Seasonality and Gradual Waning Immunity.Bulletin of mathematical biology · 2025Article
- Molecular characterization of influenza virus circulating in Nepal in the year 2019.Scientific reports · 2024Article
- Global seasonal and pandemic patterns in influenza: An application of longitudinal study designs.International statistical review = Revue internationale de statistique · 2022Article
- Role of cross-reactivity in cellular immune targeting of influenza A M1Frontiers in immunology · 2022Article
- Signatures of Cholera Outbreak during the Yemeni Civil War, 2016-2019.International journal of environmental research and public health · 2021Article
- Impact of biometeorological conditions and air pollution on influenza-like illnesses incidence in Warsaw.International journal of biometeorology · 2021Article
- Environmental factors, winter respiratory infections and the seasonal variation in heart failure admissions.Scientific reports · 2021Article
- The role of respiratory droplet physicochemistry in limiting and promoting the airborne transmission of human coronaviruses: A critical review.Environmental pollution (Barking, Essex : 1987) · 2021Review
- The burden of influenza in older adults: meeting the challenge.Aging clinical and experimental research · 2021Article
- Completeness of open access FluNet influenza surveillance data for Pan-America in 2005-2019.Scientific reports · 2021Article
- Abrupt Subsidence of Seasonal Influenza after COVID-19 Outbreak, Hong Kong, China.Emerging infectious diseases · 2020Article
- Characteristics of Seasonal Influenza Virus Activity in a Subtropical City in China, 2013-2019.Vaccines · 2020Article
- Assessing Seasonality Variation with Harmonic Regression: Accommodations for Sharp Peaks.International journal of environmental research and public health · 2020Article
- Incorporating calendar effects to predict influenza seasonality in Milwaukee, Wisconsin.Epidemiology and infection · 2019Article
- Incidence and seasonality of respiratory viruses causing acute respiratory infections in the Northern United Arab Emirates.Journal of medical virology · 2019Article
- Deploying digital health data to optimize influenza surveillance at national and local scales.PLoS computational biology · 2018Article
- Pilot study to harmonize the reported influenza intensity levels within the Spanish Influenza Sentinel Surveillance System (SISSS) using the Moving Epidemic Method (MEM).Epidemiology and infection · 2017Article
- Influenza seasonality and vaccination timing in tropical and subtropical areas of southern and south-eastern Asia.Bulletin of the World Health Organization · 2014Article
- Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
In temperate regions, influenza typically arrives with the onset of colder weather. Seasonal waves travel over large spaces covering many climatic zones in a relatively short period of time. The precise mechanism for this striking seasonal pattern is still not well understood, and the interplay of factors that influence the spread of infection and the emergence of new strains is largely unknown. The study of influenza seasonality has been fraught with problems. One of these is the ever-shifting description of illness resulting from influenza and the use of both the historical definitions and new definitions based on actual isolation of the virus. The compilation of records describing influenza oscillations on a local and global scale is massive, but the value of these data is a function of the definitions used. In this review, we argue that observations of both seasonality and deviation from the expected pattern stem from the nature of this disease. Heterogeneity in seasonal patterns may arise from differences in the behaviour of specific strains, the emergence of a novel strain, or cross-protection from previously observed strains. Most likely, the seasonal patterns emerge from interactions of individual factors behaving as coupled resonators. We emphasize that both seasonality and deviations from it may merely be reflections of our inability to disentangle signal from noise, because of ambiguity in measurement and/or terminology. We conclude the review with suggestions for new promising and realistic directions with tangible consequences for the modelling of complex influenza dynamics in order to effectively control infection.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.