Evidence map›Paper›PMID 22957127›Full record

ArticleInfection ecology & epidemiology2012

Experimental infection of three laboratory mouse stocks with a shrew origin Bartonella elizabethae strain: an evaluation of bacterial host switching potential.

Leah Colton, Hidenori Kabeya, Michael Kosoy

Abstract read
In one paragraph

Article in Infection ecology & epidemiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Evaluation of the available animal models forOne health (Amsterdam, Netherlands) · 2024
    Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Leah ColtonCenters for Disease Control and Prevention, Division of Vector-Borne Diseases, Fort Collins, CO, USA.
Hidenori Kabeya
Michael Kosoy

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBartonella elizabethae has been reported as a causative agent of human illnesses and strains of this bacterium are commonly isolated from commensal small mammals in Asia.

methodsSince the zoonotic potential of a pathogen is often related to its host switching ability, we explored the capacity of a B. elizabethae strain to host switch by subcutaneously inoculating groups of Swiss Webster, BALB/c, and C57BL/6 mice with the bacteria at a range of doses.

resultsA low number of mice in each of the three groups showed susceptibility to infection at high doses (10(5) and 10(6) bacteria), and developed bacteremias of 6-8 weeks duration.

conclusionThe capacity of this B. elizabethae strain to switch hosts can have important public health consequences for humans in areas of Asia where many small mammal populations have high bartonellae infection prevalences and live as commensals with humans.

Indexed as

ratshrewSuncus murinusVietnamzoonoses

Identifiers

PMID22957127
PMCPMC3426323

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.