ArticlePloS one2012
Response of high-sensitive C-reactive protein to catheter ablation of atrial fibrillation and its relation with rhythm outcome.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- Comparison of Myocardial Injury and Inflammation Biomarkers and Their Impact on Recurrence after Cryoballoon and Radiofrequency Ablation for Atrial Fibrillation: A Systematic Review and Meta-Analysis.Reviews in cardiovascular medicine · 2022Pooled it
- Thrombomodulin and High-Sensitive C-Reactive Protein Levels in Blood Correlate with the Development of Cerebral Infarction Among Asians.Molecular neurobiology · 2016Pooled it
- Association between C-reactive protein and atrial fibrillation recurrence after catheter ablation: a meta-analysis.Clinical cardiology · 2013Pooled it
- Risk and Protective Factors of Recurrence after Catheter Ablation for Atrial Fibrillation.Reviews in cardiovascular medicine · 2024Review
- High sensitivity C reactive protein levels and atrial fibrillation recurrence after catheter ablation for atrial fibrillation: A systematic review and meta-analysis.Journal of arrhythmia · 2023Article
- Radiofrequency ablation reduces expression of SELF by upregulating the expression of microRNA-26a/b in the treatment of atrial fibrillation.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2022Article
- Analysis of potential genetic biomarkers using machine learning methods and immune infiltration regulatory mechanisms underlying atrial fibrillation.BMC medical genomics · 2022Article
- C-reactive protein for prediction of atrial fibrillation recurrence after catheter ablation.BMC cardiovascular disorders · 2020Article
- Red blood cell distribution width as a predictor of atrial fibrillation.Journal of clinical laboratory analysis · 2018Article
- [Biomarkers and atrial fibrillation : Prediction of recurrences and thromboembolic events after rhythm control management].Herzschrittmachertherapie & Elektrophysiologie · 2018Review
- Characteristics of PR interval as predictor for atrial fibrillation: association with biomarkers and outcomes.Clinical research in cardiology : official journal of the German Cardiac Society · 2017Review
- Discordant Relationships between Systemic Inflammatory Markers and Burden of Oxidative Stress in Patients with Atrial Fibrillation.Korean circulation journal · 2017Article
- Galectin-3 in patients with atrial fibrillation undergoing radiofrequency catheter ablation.PloS one · 2015Article
- A variant of IL6R is associated with the recurrence of atrial fibrillation after catheter ablation in a Chinese Han population.PloS one · 2014Article
- Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsThis study investigated the possible association between hs-CRP as well as hs-CRP changes and rhythm outcome after AF catheter ablation.
methodsWe studied 68 consecutive patients with AF undergoing catheter ablation. hs-CRP levels were measured using commercially available assays before and 6 months after catheter ablation. Serial 7-day Holter ECGs were used to detect AF recurrences.
resultsEarly AF recurrence (ERAF, within one week) was observed in 38%, while late AF recurrence (LRAF, between 3 and 6 months) occurred in 18% of the patients. None of the baseline clinical or echocardiographic variables was predictive of ERAF or LRAF. Baseline hs-CRP measured 2.07 ± 1.1 µg/ml and was not associated with ERAF and LRAF. At 6 months, hs-CRP levels were comparable with baseline values (2.14±1.19 µg/ml, p = 0.409) and were also not related with LRAF. However, patients with LRAF showed an hs-CRP increase from 2.03 ± 0.61 to 2.62 ± 1.52 µg/ml (p = 0.028). Patients with an hs-CRP change in the upper tertile (>0.2 µg/ml) had LRAF in 32% as opposed to 11% (p = 0.042) in patients in the lower (<-0.3 µg/ml) or intermediate (-0.3-0.2 µg/ml) tertile.
conclusionsChanges in hs-CRP but not baseline hs-CRP are associated with rhythm outcome after AF catheter ablation. This finding points to a link between an inflammatory response and AF recurrence in this setting.
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Registered trials
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