ArticleCase reports in medicine2012
Neuroblastoma in the Elderly and SIADH: Case Report and Review of the Literature.
Article in Case reports in medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 18 citations in OpenAlex.
- Long-Term Survival after Surgical Resection and Radiotherapy for Anterior Mediastinal Neuroblastoma in an Older Patient: A Case Report.Surgical case reports · 2025Article
- Anterior mediastinal neuroblastoma in an adult: an additional case of a rare tumor in an unusual location with review of the literature.Diagnostic pathology · 2023Review
- Anterior Mediastinal Neuroblastoma Associated with Syndrome of Inappropriate Antidiuretic Hormone Secretion: A Morphologic, Immunohistochemical, and Genetic Case Report and Review of the Literature.International journal of surgical pathology · 2022Review
- [Mesenchymal tumors of the mediastinum].Der Pathologe · 2016Review
- The 2015 World Health Organization Classification of Tumors of the Thymus: Continuity and Changes.Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer · 2015Review
- Ataxia induced by a thymic neuroblastoma in the elderly patient.World journal of surgical oncology · 2015Article
- Neuroblastoma after childhood: prognostic relevance of segmental chromosome aberrations, ATRX protein status, and immune cell infiltration.Neoplasia (New York, N.Y.) · 2014Article
- Neuroblastoma of the elderly, an oncologist's nightmare: case presentation, literature review and SEER database analysis.Experimental hematology & oncology · 2014Article
- Neuroblastoma in early childhood: A rare case report and review of literature.Contemporary clinical dentistryArticle
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective. To report the rare case of a thymic neuroblastoma, in an elderly woman with SIADH at presentation. Methods. Clinical and biochemical data of the patient are presented and the pertinent literature is reviewed. Results. a 79-year-old woman was admitted into our department with worsening asthenia, severe hyponatremia (114.8 mEq/L), low plasma osmolarity (253 mEq/L), and inappropriate urinary sodium concentration (151 mEq/L). CT scan showed an a large solid inhomogeneous mass in the anterior mediastinum. (18)F-FDG-PET/CT showed uptake in the mass. On continuous 3% hypertonic saline infusion, sodium gradually increased without achieving normal values. The patient underwent surgery, followed by full normalization of sodium levels. Tumor cells were positive for neuroendocrine markers. Thymic neuroblastoma with SIADH was diagnosed. Conclusions. Neuroblastoma is an extremely rare tumor in the elderly. Contrary to children and younger adults, neuroblastoma in older adults is typically localized in the anterior mediastinum and is often associated with SIADH. Moreover, it has mainly local aggressiveness in this age group, without metastatic spread; thus radical surgery achieves cure in most cases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.