ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2012
Flexible cortical control of task-specific muscle synergies.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
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Who cites it
49 citing papers in PubMed, 108 citations in OpenAlex.
- Adaptation of motor unit synergies in the synergetic ankle plantarflexors in ambulatory persons with incomplete spinal cord injury.Journal of neuroengineering and rehabilitation · 2026Article
- The role of muscle synergies and task constraints on upper limb motor impairment after stroke.Experimental brain research · 2025Article
- Intermuscular coherence during arm movement changes significantly with shoulder abduction and age, but not with limb dominance.Frontiers in physiology · 2025Article
- Biomimetic versus arbitrary motor control strategies for bionic hand skill learning.Nature human behaviour · 2024Article
- Dissecting muscle synergies in the task space.eLife · 2024Article
- Muscle synergies are associated with intermuscular coherence and cortico-synergy coherence in an isometric upper limb task.Experimental brain research · 2023Article
- Virtual regression-based myoelectric hand-wrist prosthesis control and electrode site selection using no force feedback.Biomedical signal processing and control · 2023Article
- Should bionic limb control mimic the human body? Impact of control strategy on bionic hand skill learning.bioRxiv : the preprint server for biology · 2023Article
- Evidence for shared neural information between muscle synergies and corticospinal efficacy.Scientific reports · 2022Article
- Myoelectric Control Performance of Two Degree of Freedom Hand-Wrist Prosthesis by Able-Bodied and Limb-Absent Subjects.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2022Article
- Temporal control of muscle synergies is linked with alpha-band neural drive.The Journal of physiology · 2021Article
- Learning to use Muscles.Journal of human kinetics · 2021Article
- Optimal Approach for Signal Detection in Steady-State Visual Evoked Potentials in Humans Using Single-Channel EEG and Stereoscopic Stimuli.Frontiers in neuroscience · 2021Article
- When 90% of the variance is not enough: residual EMG from muscle synergy extraction influences task performance.Journal of neurophysiology · 2020Article
- The effects of motor modularity on performance, learning and generalizability in upper-extremity reaching: a computational analysis.Journal of the Royal Society, Interface · 2020Article
- Muscle Synergies and Coherence Networks Reflect Different Modes of Coordination During Walking.Frontiers in physiology · 2020Article
- Jaw Elevator Muscle Coordination during Rhythmic Mastication in Primates: Are Triplets Units of Motor Control?Brain, behavior and evolution · 2020Article
- Parkinson's Disease Exhibits Amplified Intermuscular Coherence During Dynamic Voluntary Action.Frontiers in neurology · 2020Article
- Effect of User Practice on Prosthetic Finger Control With an Intuitive Myoelectric Decoder.Frontiers in neuroscience · 2019Article
- Spasms after spinal cord injury show low-frequency intermuscular coherence.Journal of neurophysiology · 2018Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Correlation structure in the activity of muscles across movements is often interpreted as evidence for low-level, hardwired constraints on upper-limb function. However, muscle synergies may also emerge from optimal strategies to achieve high-level task goals within a redundant control space. To distinguish these contrasting interpretations, we examined the structure of muscle variability during operation of a myoelectric interface in which task constraints were dissociated from natural limb biomechanics. We found that, with practice, human subjects learned to shape patterns of covariation between arbitrary pairs of hand and forearm muscles appropriately for elliptical targets whose orientation varied on a trial-by-trial basis. Thus, despite arriving at the same average location in the effector space, performance was improved by buffering variability into those dimensions that least impacted task success. Task modulation of beta-frequency intermuscular coherence indicated that differential recruitment of divergent corticospinal pathways contributed to positive correlations among muscles. However, this feedforward mechanism could not account for negative correlations observed in the presence of visual feedback. A second experiment revealed the development of fast, target-dependent visual responses consistent with "minimum intervention" control correcting predominantly task-relevant errors. Together, these mechanisms contribute to the dynamic emergence of task-specific muscle synergies appropriate for a wide range of abstract task goals.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.