Evidence map›Paper›PMID 22956513›Full record

ArticleAmerican journal of epidemiology2012

Invited commentary: structural equation models and epidemiologic analysis.

Tyler J VanderWeele

Abstract readComment
In one paragraph

Article in American journal of epidemiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
82citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

82 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. The role of the working alliance in treatment for alcohol problems.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2015
    Trial
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  7. Causal Inference in Clinical Research: A Primer.Journal of periodontal research · 2026
    Review
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22 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Tyler J VanderWeeleDepartments of Epidemiology and Biostatistics, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA. tvanderw@hsph.harvard.edu

Funding

Bounds for direct and indirect effects with application to perinatal epidemiologyR03HD060696 · NICHD · HARVARD SCHOOL OF PUBLIC HEALTH · PI VANDERWEELE, TYLER · 2010 to 2011
$169k
NICHD NIH HHS HD060696NICHD NIH HHS R03 HD060696
6 · The paper itself

Abstract

In this commentary, structural equation models (SEMs) are discussed as a tool for epidemiologic analysis. Such models are related to and compared with other analytic approaches often used in epidemiology, including regression analysis, causal diagrams, causal mediation analysis, and marginal structural models. Several of these other approaches in fact developed out of the SEM literature. However, SEMs themselves tend to make much stronger assumptions than these other techniques. SEMs estimate more types of effects than do these other techniques, but this comes at the price of additional assumptions. Many of these assumptions have often been ignored and not carefully evaluated when SEMs have been used in practice. In light of the strong assumptions employed by SEMs, the author argues that they should be used principally for the purposes of exploratory analysis and hypothesis generation when a broad range of effects are potentially of interest.

Indexed as

Models, StatisticalWorkloadWork Schedule ToleranceFatigueFemaleHumansMaleOccupational InjuriesSleep Deprivation

Identifiers

PMID22956513
PMCPMC3530375

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.