Evidence map›Paper›PMID 22956352›Full record

ArticlePlant foods for human nutrition (Dordrecht, Netherlands)2012

Hypolipidemic and antioxidative effects of noni (Morinda citrifolia L.) juice on high- fat/cholesterol-dietary hamsters.

Yi-Ling Lin, Chung-Hsi Chou, Deng-Jye Yang, Jr-Wei Chen, Bor-Show Tzang, Yi-Chen Chen

Abstract read
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In one paragraph

Article in Plant foods for human nutrition (Dordrecht, Netherlands), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
10.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 49 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Noni (Frontiers in genetics · 2017
    Article
  5. Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Yi-Ling LinInstitute of Biochemistry and Biotechnology, Chung Shan Medical University, Taichung 402, Taiwan.
Chung-Hsi Chou
Deng-Jye Yang
Jr-Wei Chen
Bor-Show Tzang
Yi-Chen Chen
Chung Shan Medical University · TWNational Taiwan University · TWChung Shan Medical University Hospital · TWCouncil of Agriculture · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Noni juice (NJ) is rich in phytochemicals and polysaccharides. Lipid-lowering and antioxidative effects of NJ were investigated in this study. Fifty male hamsters were assigned randomly to one of the following groups: (1) normal diet and distilled water (LFCD); (2) high-fat/cholesterol diet and distilled water (HFCD); (3) HFCD and 3 ml NJ (including 0.20 g solids)/kg BW (NJ_L); (4) HFCD and 6 mL NJ (including 0.40 g solids)/kg BW (NJ_M); (5) HFCD and 9 ml NJ (including 0.60 g solids)/kg BW (NJ_H) for six weeks. NJ supplementation decreased (p < 0.05) serum triacylglycerol, cholesterol, atherogenic index, malondialdehyde levels, and hepatic lipids in HFCD hamsters, whereas serum trolox equivalent antioxidant capacity, glutathione, and fecal lipids in HFCD hamsters were increased (p < 0.05) by NJ supplementation. Although NJ supplementation downregulated (p < 0.05) sterol regulator element binding protein-1c in HFCD hamsters, it upregulated (p < 0.05) hepatic peroxisome proliferator-activated receptor-alpha and uncoupling protein 2 gene expressions in HFCD hamsters. Results demonstrate that NJ promotes cardioprotection in a high-fat/cholesterol diet.

Indexed as

Diet, High-FatPhytotherapyAnimalsAntioxidantsAtherosclerosisBeveragesCholesterol, DietaryCricetinaeDietary FatsDietary SupplementsFecesFruitGene ExpressionGlutathioneHypolipidemic AgentsIon ChannelsAntioxidantsCholesterol, DietaryDietary FatsGlutathioneHypolipidemic AgentsIon ChannelsMalondialdehydeMitochondrial ProteinsPlant PreparationsPolysaccharidesPPAR alphaSterol Regulatory Element Binding Protein 1TriglyceridesUncoupling Protein 2

Identifiers

PMID22956352
OpenAlexW2043002534

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.