ArticleChromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology2012
Chromomeres revisited.
Article in Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- The 3D genomics of lampbrush chromosomes highlights the role of active transcription in chromatin organization.Nucleic acids research · 2026Article
- Assignment of the somatic A/B compartments to chromatin domains in giant transcriptionally active lampbrush chromosomes.Epigenetics & chromatin · 2023Article
- Comparison of the somatic TADs and lampbrush chromomere-loop complexes in transcriptionally active prophase I oocytes.Chromosoma · 2022Article
- New Insights Into Chromomere Organization Provided by Lampbrush Chromosome Microdissection and High-Throughput Sequencing.Frontiers in genetics · 2020Article
- Mapping epigenetic modifications on chicken lampbrush chromosomes.Molecular cytogenetics · 2020Article
- Patterns in the genome.Heredity · 2019Review
- Herbert Macgregor (1933-2018).Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2018Article
- Epichromatin and chromomeres: a 'fuzzy' perspective.Open biology · 2018Review
- Review
- Centromeric and non-centromeric satellite DNA organisation differs in holocentric Rhynchospora species.Chromosoma · 2017Article
- Transcription of highly repetitive tandemly organized DNA in amphibians and birds: A historical overview and modern concepts.RNA biology · 2016Review
- Giant poly(A)-rich RNP aggregates form at terminal regions of avian lampbrush chromosomes.Chromosoma · 2016Article
- Determinants of Chromosome Architecture: Insulator Pairing in cis and in trans.PLoS genetics · 2016Article
- Precocious detection on amphibian oocyte lampbrush chromosomes of subtle changes in the cellular localisation of the Ro52 protein induced by in vitro culture.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2012Article
- High-resolution mapping and transcriptional activity analysis of chicken centromere sequences on giant lampbrush chromosomes.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2012Article
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1 author.
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Abstract
The history of studies on the chromomeres of lampbrush chromosomes is outlined and evidence for the nature and function of these structures is collected and summarised. Chromomeres and their associated loops on lampbrush chromosomes are not genetic units although in some special cases, they consist of specific families of repeated DNA sequences. The emergence of a chromomeric organisation coincides with the onset and intensification of transcription on lampbrush loops. Modern molecular studies have provided evidence that the chromatin of lampbrush chromomeres differs in several important respects from that of condensed metaphase chromosomes. It is in a highly dynamic state that facilitates localised transcription whilst keeping the chromosome safe from structural changes that might impede its orderly progression up to and through meiotic metaphase 1. Lampbrush chromosomes (LBCs) are a physically induced phenomenon, facilitated by the selective absence of molecular factors that would interfere with their main transcriptional role. LBC morphology is highly dynamic and driven by transcriptive activity.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.