Evidence map›Paper›PMID 22956145›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2012

Mouse models for tumor metastasis.

Shengyu Yang, J Jillian Zhang, Xin-Yun Huang

Abstract read
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed
9.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 116 citations in OpenAlex.

  1. Article
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  10. A Computational and Chemical Design Strategy for Manipulating Glycan-Protein Recognition.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  11. Article
  12. Article
  13. Nanomedicine (London, England) · 2024
    Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Advances in Preclinical PET.Seminars in nuclear medicine · 2022
    Review
  19. Article
  20. Article

10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Shengyu YangDepartment of Physiology, Cornell University Weill Medical College, New York, USA.
J Jillian Zhang
Xin-Yun Huang
Cornell University · US

Funding

Migrastatin Analogues and Inhibition of Tumor MetastasisR01CA136837 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI HUANG, XIN-YUN · 2009 to 2011
$1.0M
NCI NIH HHS R01 CA136837NCI NIH HHS R01CA136837
6 · The paper itself

Abstract

Tumor metastasis is the main cause of death of cancer patients. Here we describe two mouse models for investigating tumor metastasis. In the first spontaneous metastasis mouse model, 4T1 mouse breast tumor cells are injected into the mammary gland of host mice and the metastasis of 4T1 tumor cells into the lung are examined with a colonogenic assay. In the second experimental metastasis mouse model, luciferase-labeled MDA-MB-231 human breast tumor cells are injected into the tail vein of NOD-SCID immunodeficient mice and the colonization of MDA-MB-231 tumor cells in the lung are monitored using noninvasive bioluminescence imaging.

Indexed as

AnimalsCell Line, TumorDisease Models, AnimalFemaleMammary Neoplasms, AnimalMiceMice, Inbred BALB CNeoplasm Metastasis

Identifiers

PMID22956145
PMCPMC3674868
OpenAlexW79483467

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.