ArticleGenome research2012
What does our genome encode?
Article in Genome research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
55 citing papers in PubMed.
- "Snip, snip, cure"? Philosophical, legal and biomedical perspectives on novel somatic genomic therapies.Medicine, health care, and philosophy · 2025Article
- Active regulatory elements recruit cohesin to establish cell specific chromatin domains.Scientific reports · 2025Article
- The genetic architecture of multimodal human brain age.Nature communications · 2024Article
- Novel research and future prospects of artificial intelligence in cancer diagnosis and treatment.Journal of hematology & oncology · 2023Review
- The Genetic Architecture of Multimodal Human Brain Age.bioRxiv : the preprint server for biology · 2023Article
- Review
- Article
- The MHC in the era of next-generation sequencing: Implications for bridging structure with function.Human immunology · 2019Review
- Resolving systematic errors in widely used enhancer activity assays in human cells.Nature methods · 2018Article
- Patterns of variation in cis-regulatory regions: examining evidence of purifying selection.BMC genomics · 2018Article
- Using Chromatin Architecture to Understand the Genetics and Transcriptomics of Juvenile Idiopathic Arthritis.Frontiers in immunology · 2018Review
- Biology and Mechanisms of Action of the Vitamin D Hormone.Endocrinology and metabolism clinics of North America · 2017Review
- Estimating the prevalence of functional exonic splice regulatory information.Human genetics · 2017Review
- Precision Medicine Approaches to Diabetic Kidney Disease: Tissue as an Issue.Current diabetes reports · 2017Review
- From Clinical Standards to Translating Next-Generation Sequencing Research into Patient Care Improvement for Hepatobiliary and Pancreatic Cancers.International journal of molecular sciences · 2017Review
- Epigenetic regulation of bone cells.Connective tissue research · 2017Review
- Splendor and misery of adaptation, or the importance of neutral null for understanding evolution.BMC biology · 2016Article
- Chromatin landscapes and genetic risk in systemic lupus.Arthritis research & therapy · 2016Article
- Spatial genome organization and cognition.Nature reviews. Neuroscience · 2016Review
- Chromatin organization in pluripotent cells: emerging approaches to study and disrupt function.Briefings in functional genomics · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
In its first production phase, The ENCODE Project Consortium (ENCODE) has generated thousands of genome-scale data sets, resulting in a genomic "parts list" that encompasses transcripts, sites of transcription factor binding, and other functional features that now number in the millions of distinct elements. These data are reshaping many long-held beliefs concerning the information content of the human and other complex genomes, including the very definition of the gene. Here I discuss and place in context many of the leading findings of ENCODE, as well as trends that are shaping the generation and interpretation of ENCODE data. Finally, I consider prospects for the future, including maximizing the accuracy, completeness, and utility of ENCODE data for the community.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.