Evidence map›Paper›PMID 22955894›Full record

ArticleEuropean journal of clinical pharmacology2013

The association of ethnicity with electronically measured adherence to inhaled corticosteroids in children.

Erwin Vasbinder, Nordin Dahhan, Bart Wolf, Jan Zoer, Ellen Blankman, Diederik Bosman, Liset van Dijk, Patricia van den Bemt

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in European journal of clinical pharmacology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 32 citations in OpenAlex.

  1. Trial
  2. Article
  3. Dysfunctional breathing and its impact on asthma control in children and adolescents.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2023
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  5. Review
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  11. Determinants of longitudinal health-related quality-of-life change in children with asthma from low-income families: a report from the PROMISClinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2017
    Article
  12. Article
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Erwin VasbinderDepartment of Hospital Pharmacy, Erasmus Medical Center, Room L-030, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.
Nordin Dahhan
Bart Wolf
Jan Zoer
Ellen Blankman
Diederik Bosman
Liset van Dijk
Patricia van den Bemt
Erasmus MC · NLRijnstate Hospital · NLSint Lucas Andreas Hospital · NLEmma Kinderziekenhuis · NLUtrecht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the association of ethnicity with objectively, electronically measured adherence to inhaled corticosteroids (ICS) in a multicultural population of children with asthma in the city of Amsterdam.

methodsThe study was designed as a prospective, observational multicenter study in which adherence to ICS and potential risk factors for adherence to ICS were measured in a cohort of Moroccan and native Dutch children with asthma. Electronic adherence measurements were performed for 3 months per patient using a Real Time Medication Monitoring (RTMM) system. Ethnicity and other potential risk factors, such as socio-economic status, asthma control and parental medication beliefs, were extracted from medical records or parent interviews. The association between adherence and ethnicity was analysed using multivariate linear regression analysis.

resultsA total of 90 children (aged 1-11 years) were included in the study and data of 87 children were used for analysis. Average adherence to ICS was 49.3 %. Native Dutch children showed higher adherence to ICS than Moroccan children (55.9 vs. 42.5 %, respectively; p = 0.044, univariate analysis). After correction for confounders (>3 annual visits to the paediatric outpatient clinic, regular use of a spacer during inhalation), the final regression model showed that ethnicity was independently associated with adherence (p = 0.028).

conclusionsIn our Western European population of inner city children with asthma, poor adherence to ICS was a serious problem, and even somewhat more so in ethnic minorities. Paediatricians involved in asthma treatment should be aware of these cultural differences in medication-taking behaviour, but further studies are needed to elucidate the causal mechanism.

Indexed as

Administration, InhalationAdrenal Cortex HormonesAge FactorsAnti-Asthmatic AgentsAsthmaBlack PeopleChildChild, PreschoolChild WelfareCultural CharacteristicsEquipment DesignFemaleHealth Knowledge, Attitudes, PracticeHumansInfantLinear ModelsAdrenal Cortex HormonesAnti-Asthmatic Agents

Identifiers

PMID22955894
OpenAlexW2005330700

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.