ReviewNature reviews. Immunology2012
Consortium biology in immunology: the perspective from the Immunological Genome Project.
Review in Nature reviews. Immunology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- IL-33 expands plasma cells, disrupts germinal centers, and increases autoantibody production in mice.Nature communications · 2025Article
- Functional targeting of ILC2s and ILC3s reveals selective roles in intestinal fibrosis and homeostasis.The Journal of experimental medicine · 2025Article
- Gene Expression Analysis of (Paired) Primary and Relapsed Wilms Tumor Samples to Unravel the Underlying Factors Driving Tumor Recurrence.Cancer medicine · 2025Article
- Innateness transcriptome gradients characterize mouse T lymphocyte populations.Journal of immunology (Baltimore, Md. : 1950) · 2025Article
- Transcription factor TFII-I fine tunes innate properties of B lymphocytes.Frontiers in immunology · 2023Article
- Article
- RORγt inhibitors block both IL-17 and IL-22 conferring a potential advantage over anti-IL-17 alone to treat severe asthma.Respiratory research · 2021Article
- A basophil-neuronal axis promotes itch.Cell · 2021Article
- Post-sepsis immunosuppression depends on NKT cell regulation of mTOR/IFN-γ in NK cells.The Journal of clinical investigation · 2020Article
- Precise and Rapid Validation of Candidate Gene by Allele Specific Knockout With CRISPR/Cas9 in Wild Mice.Frontiers in genetics · 2019Article
- Targeted PET imaging strategy to differentiate malignant from inflamed lymph nodes in diffuse large B-cell lymphoma.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- The nasal methylome and childhood atopic asthma.The Journal of allergy and clinical immunology · 2017Article
- Profiling networks of distinct immune-cells in tumors.BMC bioinformatics · 2016Article
- Embracing Complexity beyond Systems Medicine: A New Approach to Chronic Immune Disorders.Frontiers in immunology · 2016Article
- Mapping the effects of drugs on the immune system.Nature biotechnology · 2016Article
- Advancing biomedical imaging.Proceedings of the National Academy of Sciences of the United States of America · 2015Review
- Utilizing population variation, vaccination, and systems biology to study human immunology.Trends in immunology · 2015Review
- Opportunities and challenges of proteomics in pediatric patients: circulating biomarkers after hematopoietic stem cell transplantation as a successful example.Proteomics. Clinical applications · 2014Review
- Digital cell quantification identifies global immune cell dynamics during influenza infection.Molecular systems biology · 2014Article
- Differential protein network analysis of the immune cell lineage.BioMed research international · 2014Article
Corrections and comments
- Erratum issuedCipoletta, Daniela [corrected to Cipolletta, Daniela]
Authors and funding
5 authors.
Funding
Abstract
Although the field has a long collaborative tradition, immunology has made less use than genetics of 'consortium biology', wherein groups of investigators together tackle large integrated questions or problems. However, immunology is naturally suited to large-scale integrative and systems-level approaches, owing to the multicellular and adaptive nature of the cells it encompasses. Here, we discuss the value and drawbacks of this organization of research, in the context of the long-running 'big science' debate, and consider the opportunities that may exist for the immunology community. We position this analysis in light of our own experience, both positive and negative, as participants of the Immunological Genome Project.
Indexed as
Identifiers
22955842What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.