ReviewPsychopharmacology2012
Emotional valence and context of social influences on drug abuse-related behavior in animal models of social stress and prosocial interaction.
Review in Psychopharmacology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
46 citing papers in PubMed.
- In the company of others: social factors alter acute alcohol effects.Psychopharmacology · 2013Trial
- Estradiol and social withdrawal in addiction: a sex-specific neuroendocrine perspective.Oxford open neuroscience · 2026Article
- The social origins of consciousness.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025Article
- Renewal of cocaine seeking using social and nonsocial contextual stimuli.Psychopharmacology · 2025Article
- Financial Risk Aversion Among Older Black and White Adults.The journals of gerontology. Series B, Psychological sciences and social sciences · 2024Article
- Paternal morphine exposure in rats reduces social play in adolescent male progeny without affecting drug-taking behavior in juvenile males or female offspring.Molecular and cellular neurosciences · 2023Article
- Maternal per- and poly-fluoroalkyl substances exposures associated with higher depressive symptom scores among immigrant women in the Chemicals in Our Bodies cohort in San Francisco.Environment international · 2023Article
- The Protective Effect of Social Reward on Opioid and Psychostimulant Reward and Relapse: Behavior, Pharmacology, and Brain Regions.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Review
- Effect of Voluntary Wheel-Running Exercise on the Endocrine and Inflammatory Response to Social Stress: Conditioned Rewarding Effects of Cocaine.Biomedicines · 2022Article
- Confronting Racism in All Forms of Pain Research: Reframing Study Designs.The journal of pain · 2022Article
- Chronic Physical and Vicarious Psychosocial Stress Alter Fentanyl Consumption and Nucleus Accumbens Rho GTPases in Male and Female C57BL/6 Mice.Frontiers in behavioral neuroscience · 2022Article
- Factors modulating the incubation of drug and non-drug craving and their clinical implications.Neuroscience and biobehavioral reviews · 2021Review
- Social vulnerabilities for substance use: Stressors, socially toxic environments, and discrimination and racism.Neuropharmacology · 2021Review
- Oxytocin Signaling as a Target to Block Social Defeat-Induced Increases in Drug Abuse Reward.International journal of molecular sciences · 2021Review
- Housing conditions during self-administration determine motivation for cocaine in mice following chronic social defeat stress.Psychopharmacology · 2021Article
- Social Interaction With Relapsed Partner Facilitates Cocaine Relapse in Rats.Frontiers in pharmacology · 2021Article
- Association Between Alexithymia, Social Support, and Duration of Methamphetamine Use Among Male Methamphetamine-Dependent Patients.Frontiers in psychiatry · 2021Article
- Adolescent Stress Reduces Adult Morphine-Induced Behavioral Sensitization in C57BL/6J Mice.Frontiers in behavioral neuroscience · 2021Article
- Role of adolescent-formed, context-drug-associations on reinstatement of drug-seeking behavior in rats.Psychopharmacology · 2020Article
- Behavioral economic demand as a unifying language for addiction science: Promoting collaboration and integration of animal and human models.Experimental and clinical psychopharmacology · 2020Review
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
rationaleSocial factors are important determinants of drug dependence and relapse.
objectivesWe reviewed pre-clinical literature examining the role of social experiences from early life through the development of drug dependence and relapse, emphasizing two aspects of these experiences: (1) whether the social interaction is appetitive or aversive and (2) whether the social interaction occurs within or outside of the drug-taking context.
methodsThe models reviewed include neonatal care, isolation, social defeat, chronic subordination, and prosocial interactions. We review results from these models in regard to effects on self-administration and conditioned place preference established with alcohol, psychostimulants, and opiates.
resultsWe suggest that in general, when the interactions occur outside of the drug-taking context, prosocial interactions are protective against drug abuse-related behaviors, whereas social stressors facilitate these behaviors. By contrast, positive or negative social interactions occurring within the drug-taking context may interact with other risk factors to enhance or inhibit these behaviors.
conclusionsDespite differences in the nature and complexity of human social behavior compared to other species, the evolving animal literature provides useful models for understanding social influences on drug abuse-related behavior that will allow for research on the behavioral and biological mechanisms involved. The models have contributed to understanding social influences on initiation and maintenance of drug use, but more research is needed to understand social influences on drug relapse.
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