Evidence map›Paper›PMID 22955288›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2013

Peripherally inserted central catheter tip position and risk of associated complications in neonates.

A Jain, P Deshpande, P Shah

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05729321 (Lock sOlutiOnS for Epicutaneo-caval Catheters in Neonates), which is not on this map. Cited by 37 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05729321 unknown statusnot on this mapstarted 2022, after this paper: background citation

Lock sOlutiOnS for Epicutaneo-caval Catheters in Neonates: a "LOOSEN" Pilot Study

Typeobservational_patient_registrySponsorFondazione Policlinico Universitario Agostino Gemelli IRCCSRan2022 to 2023Enrolled7ConditionsCatheter-related Bloodstream Infection, Preterm, Catheter Infection, Catheter ComplicationsArmsneutrox
3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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  4. [Effect of placement of peripherally inserted central catheter via the upper versus lower extremity veins: a Meta analysis].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2019
    Pooled it
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  6. Peripherally inserted central venous catheters: frequency of complications in premature newborn depends on the insertion site.Journal of perinatology : official journal of the California Perinatal Association · 2014
    Trial
  7. Inter-center variation in non-elective removal of central catheters amongst level 4 NICUs.Journal of perinatology : official journal of the California Perinatal Association · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

A JainDivision of Neonatology, Department of Pediatrics, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada. ajain@mtsinai.on.ca
P Deshpande
P Shah

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo characterize the relationship between peripherally inserted central catheters (PICC) tip positions and associated complications in neonates. STUDY

designCatheter tip position for 319 infants was classified into superior vena cava (SVC, n=131), inferior vena cava (IVC, n=72), brachiocephalic (BC, n=59), midclavicular (MC, n=49) or iliac. Duration of catheter stay and complication profile was compared between central (SVC/IVC) vs non-central PICC, and between SVC vs IVC, SVC vs BC and SVC vs MC. Kaplan-Meier survival analysis and regression models were used.

resultOverall length of catheter stay was similar between central and non-central group. Non-central catheters (n=116) had higher complication rates (47 vs 29%; P=0.001), non-elective removals (45 vs 27%; P=0.002) and shorter time to complication (6.2 vs 11.4 days; P=0.043). This difference was primarily due to the complications encountered in MC group, which had the highest rate of infiltration (P<0.001) and mechanical complications while outcomes were similar among other subgroups. Interestingly, catheter survival probability was similar in all groups for first 4 days. Rate and types of blood stream infections were not related to catheter tip position.

conclusionNon-central PICCs are associated with higher rates of infiltration and mechanical complications when the tip is in MC region. BC catheters may have comparable outcomes to SVC in neonates. A careful risk-benefit analysis is warranted when MC catheters are used in neonates.

Indexed as

Catheterization, Central VenousCatheterization, PeripheralCatheter ObstructionCatheter-Related InfectionsCanadaCatheters, IndwellingEquipment Failure AnalysisFemaleHumansInfant, NewbornInfant, PrematureIntensive Care, NeonatalKaplan-Meier EstimateMaleOutcome Assessment, Health CareRetrospective Studies

Identifiers

PMID22955288

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.