ArticleBioinformatics (Oxford, England)2012
Mendel-GPU: haplotyping and genotype imputation on graphics processing units.
Article in Bioinformatics (Oxford, England), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Advances in haplotype phasing and genotype imputation.Nature reviews. Genetics · 2026Review
- Opportunities and computational challenges in large-scale whole-genome sequencing data analysis.Journal of animal science · 2026Review
- Accelerating Wright-Fisher Forward Simulations on the Graphics Processing Unit.G3 (Bethesda, Md.) · 2017Article
- Value of Mendelian laws of segregation in families: data quality control, imputation, and beyond.Genetic epidemiology · 2014Article
- Imputation in families using a heuristic phasing approach.BMC proceedings · 2014Article
- Next Generation Statistical Genetics: Modeling, Penalization, and Optimization in High-Dimensional Data.Annual review of statistics and its application · 2014Article
- Discovering epistasis in large scale genetic association studies by exploiting graphics cards.Frontiers in genetics · 2013Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
motivationIn modern sequencing studies, one can improve the confidence of genotype calls by phasing haplotypes using information from an external reference panel of fully typed unrelated individuals. However, the computational demands are so high that they prohibit researchers with limited computational resources from haplotyping large-scale sequence data.
resultsOur graphics processing unit based software delivers haplotyping and imputation accuracies comparable to competing programs at a fraction of the computational cost and peak memory demand. AVAILABILITY: Mendel-GPU, our OpenCL software, runs on Linux platforms and is portable across AMD and nVidia GPUs. Users can download both code and documentation at http://code.google.com/p/mendel-gpu/. CONTACT: gary.k.chen@usc.edu. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.