ReviewRespiratory physiology & neurobiology2013
Chemoreceptors, baroreceptors, and autonomic deregulation in children with obstructive sleep apnea.
Review in Respiratory physiology & neurobiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
21 citing papers in PubMed.
- Impact of Obstructive Sleep Apnea-Hypopnea Syndrome Severity on Heart Rate Variability and QTc Interval in Hypertensive Patients.Medicina (Kaunas, Lithuania) · 2025Article
- Article
- Post-tonsillectomy outcomes in children with mucopolysaccharidosis and obstructive sleep apnea.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale · 2023Article
- The effect of CPAP therapy on heart rate variability in patients with obstructive sleep apnea.Sleep and biological rhythms · 2023Article
- Heart rate variability as a potential biomarker of pediatric obstructive sleep apnea resolution.Sleep · 2022Article
- Heart rate variability spectrum characteristics in children with sleep apnea.Pediatric research · 2021Article
- Cardiovascular changes in children with obstructive sleep apnea and obesity after treatment with noninvasive ventilation.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2020Article
- Obstructive Sleep Apnea and Inflammation: Proof of Concept Based on Two Illustrative Cytokines.International journal of molecular sciences · 2019Review
- Management and outcomes of obstructive sleep apnea in children with Robin sequence, a cross-sectional study.Clinical oral investigations · 2017Article
- Role of sleep quality in the metabolic syndrome.Diabetes, metabolic syndrome and obesity : targets and therapy · 2016Review
- Augmented cardiovascular responses to episodes of repetitive compared with isolated respiratory events in preschool children with sleep-disordered breathing.Pediatric research · 2015Article
- Pupillometric findings in children with obstructive sleep apnea.Sleep medicine · 2015Article
- Cardiovascular Consequences in Children with Obstructive Sleep Apnea: Is It Possible to Predict Them?Sleep · 2015Article
- Intermittent hypoxia in childhood: the harmful consequences versus potential benefits of therapeutic uses.Frontiers in pediatrics · 2015Review
- Deletion of the von Hippel-Lindau gene causes sympathoadrenal cell death and impairs chemoreceptor-mediated adaptation to hypoxia.EMBO molecular medicine · 2014Article
- Correlation of salivary alpha amylase level and adenotonsillar hypertrophy with sleep disordered breathing in pediatric subjects.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2014Article
- Unexpected benefits of intermittent hypoxia: enhanced respiratory and nonrespiratory motor function.Physiology (Bethesda, Md.) · 2014Review
- Pathogenic roles of the carotid body inflammation in sleep apnea.Mediators of inflammation · 2014Review
- Central and peripheral factors contributing to obstructive sleep apneas.Respiratory physiology & neurobiology · 2013Review
- Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Obstructive sleep apnea (OSA) is highly prevalent sleep disorder of breathing in both adults and children that is fraught with substantial cardiovascular morbidities, the latter being attributable to a complex interplay between intermittent hypoxia (IH), episodic hypercapnia, recurrent large intra-thoracic pressure swings, and sleep disruption. Alterations in autonomic nervous system function could underlie the perturbations in cardiovascular, neurocognitive, immune, endocrine and metabolic functions that affect many of the patients suffering from OSA. Although these issues have received substantial attention in adults, the same has thus far failed to occur in children, creating a quasi misperception that children are protected. Here, we provide a critical overview of the evidence supporting the presence of autonomic nervous system (ANS) perturbations in children with OSA, draw some parallel assessments to known mechanisms in rodents and adult humans, particularly, peripheral and central chemoreceptor and baroreceptor pathways, and suggest future research directions.
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Registered trials
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