ArticleBMC musculoskeletal disorders2012
A prospective study of the impact of musculoskeletal pain and radiographic osteoarthritis on health related quality of life in community dwelling older people.
Article in BMC musculoskeletal disorders, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 67 citations in OpenAlex.
- Efficacy and safety of S-flurbiprofen plaster in knee osteoarthritis patients: A 2-week randomized controlled Phase III clinical trial compared to diclofenac gel.International journal of rheumatic diseases · 2022Trial
- Short- or Long-Term Treatment of Spinal Disability in Older Adults With Manipulation and Exercise.Arthritis care & research · 2019Trial
- A mixed-methods study of patient and healthcare professional perceptions of care pathways for knee osteoarthritis.BMC primary care · 2024Article
- Article
- Effects of Circuit Training on Patients with Knee Osteoarthritis: A Systematic Review and Meta-Analysis.Healthcare (Basel, Switzerland) · 2022Review
- The Pain Medicine Curriculum Framework-structured integration of pain medicine education into the medical curriculum.Frontiers in pain research (Lausanne, Switzerland) · 2022Review
- A Comparative study of osteoarthritic knee patients between urban and rural areas in knee severity and quality of life.Health psychology research · 2022Article
- Vitamin D levels and pain outcomes in adolescent idiopathic scoliosis patients undergoing spine fusion.Spine deformity · 2021Article
- Falling risk in patients with end-stage knee osteoarthritis.Clinical rheumatology · 2021Review
- LncRNA NEAT1 regulates chondrocyte proliferation and apoptosis via targeting miR-543/PLA2G4A axis.Human cell · 2021Article
- Article
- Lifetime occupation is not associated with radiographic osteoarthritis of the first metatarsophalangeal joint in a cohort study of UK women.Journal of foot and ankle research · 2020Article
- Does the implementation of a care pathway for patients with hip or knee osteoarthritis lead to fewer diagnostic imaging and referrals by general practitioners? A pre-post-implementation study of claims data.BMC family practice · 2019Observational
- Promoting mobility and healthy aging in men: a narrative review.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2019Review
- Change in quality of life among community-dwelling older adults: population-based longitudinal study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2019Article
- Pain, Physical Function, Radiographic Features, and Quality of Life in Knee Osteoarthritis Agricultural Workers Living in Rural Population.Pain research & management · 2019Article
- Validity of the central sensitization inventory with measures of sensitization in people with knee osteoarthritis.Clinical rheumatology · 2018Article
- Contribution of central and peripheral risk factors to prevalence, incidence and progression of knee pain: a community-based cohort study.Osteoarthritis and cartilage · 2018Article
- Pain medicine content, teaching and assessment in medical school curricula in Australia and New Zealand.BMC medical education · 2018Article
- Knee pain and health-related quality of life among older patients with different knee osteoarthritis severity in Saudi Arabia.PloS one · 2018Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPain and radiographic changes are common in persons with osteoarthritis, but their relative contributions to quality of life are unknown.
methodsProspective cohort study of 1098 men and women aged 50-80 years, randomly selected from the electoral roll. Participants were interviewed at baseline and approximately 2.6 and five years later. Participants self-reported prior diagnosis of arthritis and presence of joint pain. Joint space narrowing (JSN) and osteophytes at the hip and knee were assessed by X-ray. Quality of life (QoL) was assessed using the Assessment of QoL (AQoL) instrument. Data was analysed using linear regression and mixed modelling.
resultsThe median AQoL score at baseline was 7.0, indicating very good QoL. Prevalence of pain ranged from 38-62%. Over five years of observation, pain in the neck, shoulders, back, hips, hands, knees and feet were all independently and negatively associated with QoL, in a dose-response relationship. Diagnosed osteoarthritis at all sites was associated with poorer QoL but after adjustment for pain, this only remained significant at the back. Radiographic OA was not associated with QoL. While AQoL scores declined over five years, there was no evidence of an interaction between pain and time.
conclusionsPain is common in older adults, is stable over time, and the strongest musculoskeletal correlate of QoL. It also mediates the association between diagnosed OA and QoL. Since the same factors were associated with quality of life over time as at baseline, this suggests that quality of life tracks over a five year period.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.