Evidence map›Paper›PMID 22954275›Full record

ReviewClinics in perinatology2012

The pulmonary circulation in neonatal respiratory failure.

Satyan Lakshminrusimha

Registry-linked trialAbstract readReview
In one paragraph

Review in Clinics in perinatology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07322133 (Dopamine vs. Norepinephrine in Term and Late Preterm Neonates With Hypoxemic Respiratory Failure and Systemic Hypotension Due to Pulmonary Hypertension), which is not on this map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07322133 phase4recruitingnot on this mapstarted 2026, after this paper: background citation

Dopamine vs. Norepinephrine in Term and Late Preterm Neonates With Hypoxemic Respiratory Failure and Systemic Hypotension Due to Pulmonary Hypertension: A Pilot Trial

TypeinterventionalSponsorUniversity of California, DavisRan2026 to 2027Enrolled30ConditionsHypotension and Shock, Pulmonary Hypertension of the Newborn (PPHN), Hypoxemic Respiratory FailureArmsDopamine administration, Norepinephrine
3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 103 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Physiology-guided vasoactive therapy in neonates: rethinking dopamine as first-line.Journal of perinatology : official journal of the California Perinatal Association · 2025
    Review
  9. Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Balloon Atrial Septostomy: The Balloon Size Doesn't Matter?!CJC pediatric and congenital heart disease · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Satyan LakshminrusimhaDivision of Neonatology, Women and Children's Hospital of Buffalo, State University of New York at Buffalo, 219 Bryant Street, Buffalo, NY 14222, USA. slakshmi@buffalo.edu
Women & Children's Hospital of Buffalo · US

Funding

Optimal Oxygenation in Neonatal Lung InjuryR01HD072929 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Satyanarayana Lakshminrusimha · 2012 to 2026
$5.4M
Antenatal Betamethasone in Late Preterm Gestation LambsR03HD060138 · NICHD · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI LAKSHMINRUSIMHA, SATYANARAYANA · 2009 to 2010
$159k
NICHD NIH HHS R01 HD072929NICHD NIH HHS R03 HD060138
6 · The paper itself

Abstract

The pulmonary circulation rapidly adapts at birth to establish lungs as the site of gas exchange. Abnormal transition at birth and/or parenchymal lung disease can result in neonatal hypoxemic respiratory failure. This article reviews the functional changes in pulmonary hemodynamics and structural changes in pulmonary vasculature secondary to (1) normal and abnormal transition at birth, and (2) diseases associated with neonatal hypoxemic respiratory failure. Various management strategies to correct respiratory failure are also discussed.

Indexed as

Administration, InhalationAnimalsHemodynamicsHumansHypoxiaInfant, NewbornIntensive Care Units, NeonatalNitric OxidePulmonary CirculationPulmonary Gas ExchangeRespiratory InsufficiencyVascular ResistanceNitric Oxide

Identifiers

PMID22954275
PMCPMC3598629
OpenAlexW2044343613

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.