ArticlePloS one2012
Comparative metagenomics of toxic freshwater cyanobacteria bloom communities on two continents.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
64 citing papers in PubMed.
- Investigation of cyanobacteria-hosted antibiotic resistance genes in cyanoHAB-impacted drinking water sources.Environmental science and pollution research international · 2026Article
- Spatio-Temporal Resolution of Microbial Functions and Taxa Associated With Cyanobacterial Harmful Algae Blooms Along a 500-Km Aquatic Continuum in the Lake Erie Watershed.Environmental microbiology · 2025Article
- Co-Occurrence of Toxic Bloom-Forming CyanobacteriaToxins · 2025Article
- Article
- Microcystin shapes theISME communications · 2025Article
- Microbial diversity, genomics, and phage-host interactions of cyanobacterial harmful algal blooms.mSystems · 2024Article
- Microbiome analysis revealsApplied and environmental microbiology · 2024Article
- Transdisciplinary approaches for the study of cyanobacteria and cyanotoxins.Current research in microbial sciences · 2024Article
- Soil microbial gene expression in an agricultural ecosystem varies with time and neonicotinoid seed treatments.Microbiology (Reading, England) · 2023Article
- Abundance trade-offs and dominant taxa maintain the stability of the bacterioplankton community underlyingFrontiers in microbiology · 2023Article
- Metagenomic and Metatranscriptomic Insights into Population Diversity ofApplied and environmental microbiology · 2022Article
- Time after time: detecting annual patterns in stream bacterial biofilm communities.Environmental microbiology · 2022Article
- Metagenomics Analysis to Investigate the Microbial Communities and Their Functional Profile During Cyanobacterial Blooms in Lake Varese.Microbial ecology · 2022Article
- Long-Term Warming of Baltic Sea Coastal Waters Affects Bacterial Communities in Bottom Water and Sediments Differently.Frontiers in microbiology · 2022Article
- How sediment bacterial community shifts along the urban river located in mining city.Environmental science and pollution research international · 2021Article
- Article
- Biosynthesis of a sulfated exopolysaccharide, synechan, and bloom formation in the model cyanobacteriumeLife · 2021Article
- Impact of cyanobacterial bloom on microbiomes of freshwater lakes.Journal of biosciences · 2021Article
- Genomic signatures of Lake Erie bacteria suggest interaction in the Microcystis phycosphere.PloS one · 2021Article
- Covariance of Phytoplankton, Bacteria, and Zooplankton Communities WithinFrontiers in microbiology · 2021Article
4 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Toxic cyanobacterial blooms have persisted in freshwater systems around the world for centuries and appear to be globally increasing in frequency and severity. Toxins produced by bloom-associated cyanobacteria can have drastic impacts on the ecosystem and surrounding communities, and bloom biomass can disrupt aquatic food webs and act as a driver for hypoxia. Little is currently known regarding the genomic content of the Microcystis strains that form blooms or the companion heterotrophic community associated with bloom events. To address these issues, we examined the bloom-associated microbial communities in single samples from Lake Erie (North America), Lake Tai (Taihu, China), and Grand Lakes St. Marys (OH, USA) using comparative metagenomics. Together the Cyanobacteria and Proteobacteria comprised >90% of each bloom bacterial community sample, although the dominant phylum varied between systems. Relative to the existing Microcystis aeruginosa NIES 843 genome, sequences from Lake Erie and Taihu revealed a number of metagenomic islands that were absent in the environmental samples. Moreover, despite variation in the phylogenetic assignments of bloom-associated organisms, the functional potential of bloom members remained relatively constant between systems. This pattern was particularly noticeable in the genomic contribution of nitrogen assimilation genes. In Taihu, the genetic elements associated with the assimilation and metabolism of nitrogen were predominantly associated with Proteobacteria, while these functions in the North American lakes were primarily contributed to by the Cyanobacteria. Our observations build on an emerging body of metagenomic surveys describing the functional potential of microbial communities as more highly conserved than that of their phylogenetic makeup within natural systems.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.