ArticlePloS one2012
Ratio between negative and positive lymph nodes is suitable for evaluation the prognosis of gastric cancer patients with positive node metastasis.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Application value of gastric contrast ultrasonography in gastric tumors.Insights into imaging · 2026Review
- Impact of the extent of negative lymph nodes in gastric adenocarcinoma undergoing primary surgical resection: An institutional report.Journal of the Chinese Medical Association : JCMA · 2021Article
- Ratio between negative and positive lymph nodes is a novel prognostic indicator for patients with esophageal cancer: A Surveillance, Epidemiology and End Results database analysis.Thoracic cancer · 2020Article
- Impact of examined lymph node count on staging and long-term survival of patients with node-negative stage III gastric cancer: a retrospective study using a Chinese multi-institutional registry with Surveillance, Epidemiology, and End Results (SEER) data validation.Annals of translational medicine · 2020Article
- Impact of the number of examined lymph nodes on stage migration in node-negative gastric cancer patients: a Chinese multi-institutional analysis with propensity score matching.Annals of translational medicine · 2020Article
- Outcomes after completion total gastrectomy for gastric remnant cancer: experience from a Canadian tertiary centre.Canadian journal of surgery. Journal canadien de chirurgie · 2018Article
- Impact of lymph node ratio on survival in stage III ovarian high-grade serous cancer: a Turkish Gynecologic Oncology Group study.Journal of gynecologic oncology · 2018Article
- Prognostic value of number of negative lymph node in patients with stage II and IIIa non-small cell lung cancer.Oncotarget · 2017Article
- Article
- Subtotal gastrectomy with conventional D2 lymphadenectomy for carcinoma of the distal gastric portion: A retrospective cohort study on clinical outcomes.Annals of medicine and surgery (2012) · 2016Article
- Prognostic value of number of examined lymph nodes in patients with node-negative gastric cancer.World journal of gastroenterology · 2014Article
- Digestive cancer surgery in the era of sentinel node and epithelial-mesenchymal transition.World journal of gastroenterology · 2013Review
- Impact of lymph node ratio on the survival of patients with hypopharyngeal squamous cell carcinoma: a population-based analysis.PloS one · 2013Article
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8 authors.
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No grant is acknowledged in the PubMed record.
Abstract
objectiveTo date, there is no consensus to evaluate the most appropriate category of the nodal metastasis for precise predication the prognosis of gastric cancer patients with positive node metastasis after curative surgery.
methodsWe retrospectively analyzed the clinicopathologic characteristics and overall survival (OS) of 299 gastric cancer patients with positive node metastasis after curative surgery for evaluation the optimal category of the nodal metastasis.
resultsWith the univariate and multivariate survival analyses, the depth of primary tumor invasion was identified as the independent predicators with the OS of 299 gastric cancer patients with nodal metastasis postoperatively, as were the number of positive lymph nodes (PLNs), the number of negative lymph nodes (NLNs), and the ratio between negative and positive lymph nodes (RNPL). The RNPL was identified to be more suitable for predication the OS of gastric cancer patients with positive node metastasis than the ratio between positive and dissected lymph nodes (RPDL) by using the stratum procedure of survival analysis. Besides, we found both PLNs and NLNs were independently correlated with OS of gastric cancer patients with nodal metastasis when RNPL, instead of RPDL, was controlled in the partial correlation model.
conclusionsRNPL, a new category of the nodal metastasis, was suitable for predication the OS of gastric cancer patients with nodal metastasis after curative resection, as were the PLNs, and NLNs.
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