ArticleIranian journal of psychiatry2011
Quality of Life and the Associated Psychological Factors in Caregivers of Children with PKU.
Article in Iranian journal of psychiatry, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- Is Phenylalanine Restricted Dietary Treatment in Phenylketonuria Associated with Disordered Eating: A Systematic Review.Nutrients · 2026Pooled it
- Invisible but central: family caregiving as the hidden infrastructure of pediatric PKU-an integrative review.Systematic reviews · 2026Pooled it
- Being the Pillar for Children with Rare Diseases-A Systematic Review on Parental Quality of Life.International journal of environmental research and public health · 2021Pooled it
- Relationship Between Depressive Symptoms and Quality of Life in Family Caregivers of Dependent Children: A Systematic Review with Meta-Analysis.Healthcare (Basel, Switzerland) · 2026Review
- Capability wellbeing of parents caring for children with rare diseases: a national cross-sectional study.BMC public health · 2025Article
- The impact of 22q11.2 deletion syndrome on caregivers: assessing quality of life and burden.Orphanet journal of rare diseases · 2025Article
- What is known about patients' quality of life with Phenylketonuria and their caregivers? A scoping review.Orphanet journal of rare diseases · 2024Article
- Transitioning of protein substitutes in patients with phenylketonuria: a pilot study.Frontiers in nutrition · 2024Article
- Quality of life among caregivers of patients with severe mental illness in northwest Ethiopia, 2022: an institutional-based cross-sectional study.Frontiers in psychiatry · 2024Article
- Professional activity, gender and disease-related emotions: The impact on parents' experiences in caring for children with phenylketonuria.Molecular genetics and metabolism reports · 2023Article
- Neuropsychological and quality of life outcomes in PKU patients: expert recommendations of assessment tools in Brazil.Arquivos de neuro-psiquiatria · 2023Review
- Parent's Perception of the Types of Support Given to Families with an Infant with Phenylketonuria.Nutrients · 2023Article
- Health Related Quality of Life of Caregivers of Children and Adolescents With Phenylketonuria: A Systematic Review.Global pediatric health · 2021Review
- Effects of Empowerment Program on the Burden of Care in Mothers of Children with Phenylketonuria.Iranian journal of child neurology · 2019Article
- Parenting a Child with Phenylketonuria: An Investigation into the Factors That Contribute to Parental Distress.JIMD reports · 2018Article
- Treatment Adherence and Psychological Wellbeing in Maternal Carers of Children with Phenylketonuria (PKU).JIMD reports · 2017Article
- Depression and anxiety among parents of phenylketonuria children.Neurosciences (Riyadh, Saudi Arabia) · 2015Article
- The prevalence of psychological impact on caregivers of hospitalized patients: The forgotten part of the equation.Qatar medical journal · 2015Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe main objective of this study was to investigate the association of psychological factors and life stressors with quality of life in caregivers of children with PKU.
methodsParticipants were caregivers of children with PKU who were referred to a child and adolescent consultation-liaison psychiatry clinic for a clinical follow up. Their demographic characteristics were recorded at first. WHOQOL-BREF and Depression-Anxiety-Stress Scale (DASS) were used to assess quality of life, depression, anxiety and stress in participants. Data analysis was performed using SPSS-11.5 statistical software.
resultsA total number of 49 caregivers were enrolled for the study. The mean age of participants and their children were 35.63±8.82, and 9.84±6.62 respectively. Of the participants, 59.2% were mothers and 40.8% were fathers. Of the children, 51% were girls and 49% were boys. According to the results, 57.1, 50.1 and 57.1 percent of the participants had mild to severe levels of depression, anxiety and stress scores respectively. The most associated factors with quality of life were as follows: caregivers' occupation; anxiety; and depression mean scores.
conclusionResults of the current study showed that caregivers of children with PKU have lower levels of quality of life in comparison with the general population; and the most correlated factors with quality of life were the caregivers' occupation (especially unemployment), and high levels of depression and anxiety.
Indexed as
Identifiers
22952524PMC3395945W2189462636What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.