Evidence map›Paper›PMID 22952395›Full record

ReviewCold Spring Harbor perspectives in biology2012

Adipogenesis.

Kelesha Sarjeant, Jacqueline M Stephens

Registry-linked trialAbstract readReview
In one paragraph

Review in Cold Spring Harbor perspectives in biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06703086 (Gene Modulation of NLRP3, IL-1β and TNF-α in Peripheral Blood of Patients With Exogenous Obesity Treated With Berberine), which is not on this map. Cited by 187 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
187citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06703086 nacompletednot on this mapstarted 2019, after this paper: background citation

Gene Modulation of NLRP3, IL-1β and TNF-α in Peripheral Blood of Patients With Exogenous Obesity Treated With Berberine

TypeinterventionalSponsorNational Polytechnic Institute, MexicoRan2019 to 2020Enrolled120ConditionsObesity, Overweight, BerberineArmsBerberine Hydrochloride group, nutritional plan, controlled moderate aerobic exercise
3 · Its place in the literature

Who cites it

187 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Review
  6. Review
  7. Adipogenesis Under Leptin Control: Mechanisms and Model-Specific Effects.International journal of molecular sciences · 2026
    Review
  8. Review
  9. Article
  10. Article
  11. International journal of medical sciences · 2026
    Article
  12. Lipid Metabolism in Parasitoids and Parasitized Hosts.Advances in experimental medicine and biology · 2026
    Review
  13. Article
  14. Extracellular Vesicles fromInternational journal of molecular sciences · 2025
    Article
  15. Coixol and Sinigrin fromPharmaceuticals (Basel, Switzerland) · 2025
    Article
  16. Review
  17. The Role of theInternational journal of molecular sciences · 2025
    Review
  18. Review
  19. Article
  20. Article

127 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Kelesha SarjeantDepartment of Biological Sciences, Louisiana State University, Baton Rouge, Louisiana 70803, USA.
Jacqueline M Stephens

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adipose tissue is an important site for lipid storage, energy homeostasis, and whole-body insulin sensitivity. It is important to understand the mechanisms involved in adipose tissue development and function, which can be regulated by the endocrine actions of various peptide and steroid hormones. Recent studies have revealed that white and brown adipocytes can be derived from distinct precursor cells. This review will focus on transcriptional control of adipogenesis and its regulation by several endocrine hormones. The general functions and cellular origins of adipose tissue and how the modulation of adipocyte development pertains to metabolic disease states will also be considered.

Indexed as

Adipocytes, BrownAdipocytes, WhiteAdipogenesisAdipose TissueAnimalsGene Regulatory NetworksHumansMetabolic DiseasesModels, BiologicalSignal Transduction

Identifiers

PMID22952395
PMCPMC3428766

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.