Evidence map›Paper›PMID 22952289›Full record

ArticleEuropean journal of preventive cardiology2014

Smoking cessation interventions following acute coronary syndrome: a missed opportunity?

Rachael Boggon, Adam Timmis, Harry Hemingway, Sunil Raju, Franco Mondello Malvestiti, Tjeerd P Van Staa

Abstract read
In one paragraph

Article in European journal of preventive cardiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Smoking cessation for secondary prevention of cardiovascular disease.The Cochrane database of systematic reviews · 2022
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Social Smoking Environment and Associations With Cardiac Rehabilitation Attendance.Journal of cardiopulmonary rehabilitation and prevention · 2021
    Article
  6. Is Weight Gain Inevitable for Patients Trying to Quit Smoking as Part of Cardiac Rehabilitation?International journal of environmental research and public health · 2020
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rachael BoggonGeneral Practice Research Database, MHRA, London, UK.
Adam TimmisBarts and the London School of Medicine and Dentistry, London, UK.
Harry HemingwayDepartment of Epidemiology & Public Health, University College London, UK.
Sunil RajuPfizer Ltd, Sandwich, UK.
Franco Mondello MalvestitiPfizer Ltd, Sandwich, UK.
Tjeerd P Van StaaGeneral Practice Research Database, MHRA, London, UK tjeerd.vanstaa@mhra.gsi.gov.uk.

Funding

Department of Health RP-PG-0407-10314Wellcome Trust 086091Wellcome Trust 086091/Z/08/Z
6 · The paper itself

Abstract

backgroundIt is recommended that general practitioners (GPs) offer cessation advice and pharmacological interventions to smokers with acute coronary syndrome (ACS). The study objective was to describe the extent to which this is done, and to describe outcomes by smoking status.

designPatients aged 30+ hospitalised for troponin-positive ACS from 2002 to 2009, discharged home alive, were identified in the Myocardial Ischaemia National Audit Project registry. Patient data were linked to the General Practice Research Database, Hospital Episode Statistics, and Office of National Statistics mortality data, enabling a unique perspective of longitudinal smoking data. Patients who smoked prior to the hospitalisation had GP interventions and quitting status established in the 3 months following discharge, and were followed up for major clinical outcomes.

methodsThe outcomes evaluated included death, repeat ACS, stroke, heart failure, and major adverse cardiac events (MACE).

resultsOf the 4834 patients included, 965 (20%) were smokers at the time of their ACS. After the ACS event, only 225 (24%) received any GP smoking intervention within 3 months, with 82 (9%) receiving advice only, and 143 (15%) receiving a pharmacological intervention. Patients who quit (320; 33%) were at a decreased risk of mortality (relative risk (RR) 0.49; 95% confidence interval (CI) 0.35-0.69) and MACE (RR 0.61; 0.46-0.80) compared with patients who did not.

conclusionsWhilst a high proportion of patients with ACS are smokers, there is a low level of GP cessation intervention following hospital discharge. This missed opportunity of patient care is important given the decreased risk of mortality and MACE found amongst those who quit.

Indexed as

Smoking CessationAcute Coronary SyndromeAdultAgedAged, 80 and overFemaleHeart FailureHumansMaleMiddle AgedRetrospective StudiesStrokeacute coronary syndromecessationgeneral practiceheart failuremortalitySmokingstroke

Identifiers

PMID22952289
PMCPMC4475793

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.