ArticleProceedings. Biological sciences2012
The yield of experimental yeast populations declines during selection.
Article in Proceedings. Biological sciences, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Effects of resource packaging on the adaptative and pleiotropic consequences of evolution.NPJ systems biology and applications · 2025Article
- Trait and plasticity evolution under competition and mutualism in evolving pairwise yeast communities.PloS one · 2025Article
- Convergent genetic adaptation ofFrontiers in molecular biosciences · 2024Article
- Trade-offs predicted by metabolic network structure give rise to evolutionary specialization and phenotypic diversification.Molecular biology and evolution · 2022Article
- Identification of Evolutionary Trajectories Associated with Antimicrobial Resistance Using Microfluidics.ACS infectious diseases · 2022Article
- Selection for Cell Yield Does Not Reduce Overflow Metabolism in Escherichia coli.Molecular biology and evolution · 2022Article
- Dynamics and variability in the pleiotropic effects of adaptation in laboratory budding yeast populations.eLife · 2021Article
- Hidden paths to endless forms most wonderful: Complexity of bacterial motility shapes diversification of latent phenotypes.BMC evolutionary biology · 2020Article
- Application of simultaneous selective pressures slows adaptation.Evolutionary applications · 2020Article
- Evolution of Microbial Growth Traits Under Serial Dilution.Genetics · 2020Article
- Feedback between environment and traits under selection in a seasonal environment: consequences for experimental evolution.Proceedings. Biological sciences · 2018Article
- Trade-offs between microbial growth phases lead to frequency-dependent and non-transitive selection.Proceedings. Biological sciences · 2018Article
- Accelerating Mutational Load Is Not Due to Synergistic Epistasis or Mutator Alleles in Mutation Accumulation Lines of Yeast.Genetics · 2016Article
- In silico evolution of diauxic growth.BMC evolutionary biology · 2015Article
- Metabolism at evolutionary optimal States.Metabolites · 2015Review
- An evolutionary perspective on the Crabtree effect.Frontiers in molecular biosciences · 2014Article
- Patterns and dynamics of rapid local adaptation and sex in varying habitat types in rotifers.Ecology and evolution · 2013Article
- Availability of public goods shapes the evolution of competing metabolic strategies.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
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3 authors.
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Abstract
The trade-off between growth rate and yield can limit population productivity. Here we tested for this life-history trade-off in replicate haploid and diploid populations of Saccharomyces cerevisiae propagated in glucose-limited medium in batch cultures for 5000 generations. The yield of single clones isolated from the haploid lineages, measured as both optical and population density at the end of a growth cycle, declined during selection and was negatively correlated with growth rate. Initially, diploid populations did not pay this cost of adaptation but haploidized after about 1000-3000 generations of selection, and this ploidy transition was associated with a decline in yield caused by reduced cell size. These results demonstrate the experimental evolution of a trade-off between growth rate and yield, caused by antagonistic pleiotropy, during adaptation in haploids and after an adaptive transition from diploidy to haploidy.
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