Evidence map›Paper›PMID 22951337›Full record

ArticlePsychiatry research2012

Which came first, delusions or hallucinations? An exploration of clinical differences among patients with first-episode psychosis based on patterns of emergence of positive symptoms.

Michael T Compton, Amy A Potts, Claire Ramsay Wan, Dawn Flosnik Ionescu

Abstract read
In one paragraph

Article in Psychiatry research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Michael T ComptonThe George Washington University School of Medicine and Health Sciences, Department of Psychiatry and Behavioral Sciences, Washington, DC 20037, USA.mcompton@mfa.gwu.edu
Amy A Potts
Claire Ramsay Wan
Dawn Flosnik Ionescu

Funding

First-Episode Psychosis and Pre-Onset Cannabis UseR01MH081011 · NIMH · GEORGE WASHINGTON UNIVERSITY · PI MYERS, NEELY A · 2008 to 2012
$1.7M
Correlates of Duration of Initial Untreated PsychosisK23MH067589 · NIMH · EMORY UNIVERSITY · PI COMPTON, MICHAEL T · 2004 to 2008
$817k
NIMH NIH HHS K23 MH067589NIMH NIH HHS K23MH067589NIMH NIH HHS R01 MH081011
6 · The paper itself

Abstract

Remarkably little is known about patterns of emergence of specific symptoms in the early course of nonaffective psychotic disorders. Some 159 well-characterized first-episode psychosis patients were categorized into those with: (1) delusions only (n=29, 18.2%); (2) delusions that emerged at least 1 month before hallucinations (n=31, 19.5%); (3) hallucinations that began at least 1 month before delusions (n=26, 16.4%); and (4) delusions and hallucinations that emerged concomitantly, within the same month (n=73, 45.9%). These four groups were compared across a number of clinical features, including duration of untreated psychosis, symptom severity, insight, and functioning, while controlling for potential confounders. Patients with delusions and hallucinations emerging within the same month had a shorter duration of untreated psychosis than those in whom one psychotic symptom emerged greater than one month before the other. The delusions-only group had significantly less severe positive, negative, and general psychopathology symptom scores, as well as better social and occupational functioning. Replication and further elucidation of specific patterns of symptom emergence would deepen the field's understanding of early-course phenomenology, and may inform efforts to improve upon nosology, prognostication, and treatment selection.

Indexed as

AdolescentAdultCross-Sectional StudiesDelusionsFemaleHallucinationsHumansMalePrognosisPsychiatric Status Rating ScalesPsychotic DisordersSeverity of Illness Index

Identifiers

PMID22951337
PMCPMC3513589

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.