ArticleParasites & vectors2012
Babesia spp. and Anaplasma phagocytophilum in questing ticks, ticks parasitizing rodents and the parasitized rodents--analyzing the host-pathogen-vector interface in a metropolitan area.
Article in Parasites & vectors, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
61 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Anaplasma Phagocytophilum, a Zoonotic Vector-Borne Bacterial Species in Rodents and Its Associated Tick Vector: Systematic Review.Veterinary medicine and science · 2025Pooled it
- Global meta-analysis onPathogens and global health · 2022Pooled it
- Infection rates, species diversity, and distribution of zoonotic Babesia parasites in ticks: a global systematic review and meta-analysis.Parasitology research · 2022Pooled it
- Habitat-Specific Patterns of Tick-Borne Pathogens in Urban and Suburban Landscapes.Pathogens (Basel, Switzerland) · 2026Article
- From reservoirs to ecological integrators: the role of EuropeanFrontiers in veterinary science · 2026Review
- Country-wide assessment of tick-borne pathogens collected in ticks between 2021 and 2024 in Germany, with a focus onOne health (Amsterdam, Netherlands) · 2025Article
- Molecular detection and characterization ofInternational journal for parasitology. Parasites and wildlife · 2025Article
- Temporal Changes in Tick-Borne Pathogen Prevalence in Questing Ixodes ricinus Across Different Habitats in the North-Eastern Italian Alps.MicrobiologyOpen · 2024Article
- First molecular detection ofInternational journal for parasitology. Parasites and wildlife · 2024Article
- Coinfection ofPathogens (Basel, Switzerland) · 2024Review
- Article
- Molecular Detection ofVeterinary medicine international · 2024Article
- Canine Babesiosis Caused by LargeAnimals : an open access journal from MDPI · 2023Review
- Is babesiosis a rare zoonosis in Spain? Its impact on the Spanish Health System over 23 years.PloS one · 2023Article
- Occurrence ofMicroorganisms · 2022Article
- Detection and molecular identification of Anaplasma phagocytophilum and Babesia spp. infections in Hyalomma aegyptium ticks in Tunisia.Archives of microbiology · 2022Article
- Article
- Sympatric occurrence of Ixodes ricinus with Dermacentor reticulatus and Haemaphysalis concinna and the associated tick-borne pathogens near the German Baltic coast.Parasites & vectors · 2022Article
- A Review of Zoonotic Babesiosis as an Emerging Public Health Threat in Asia.Pathogens (Basel, Switzerland) · 2021Review
- Occurrence of juvenile Dermacentor reticulatus ticks in three regions in Poland: the final evidence of the conquest.Parasites & vectors · 2021Article
1 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aims of this study were to evaluate the host-tick-pathogen interface of Babesia spp. and Anaplasma phagocytophilum in restored areas in both questing and host-attached Ixodes ricinus and Dermacentor reticulatus and their small mammalian hosts.
methodsQuesting ticks were collected from 5 sites within the city of Leipzig, Germany, in 2009. Small mammals were trapped at 3 of the 5 sites during 2010 and 2011. DNA extracts of questing and host-attached I. ricinus and D. reticulatus and of several tissue types of small mammals (the majority bank voles and yellow-necked mice), were investigated by PCR followed by sequencing for the occurrence of DNA of Babesia spp. and by real-time PCR for A. phagocytophilum. A selected number of samples positive for A. phagocytophilum were further investigated for variants of the partial 16S rRNA gene. Co-infection with Rickettsia spp. in the questing ticks was additionally investigated.
results4.1% of questing I. ricinus ticks, but no D. reticulatus, were positive for Babesia sp. and 8.7% of I. ricinus for A. phagocytophilum. Sequencing revealed B. microti, B. capreoli and Babesia spp. EU1 in Leipzig and sequence analysis of the partial 16S RNA gene of A. phagocytophilum revealed variants either rarely reported in human cases or associated with cervid hosts. The statistical analysis revealed significantly less ticks infected with A. phagocytophilum in a city park in Leipzig as compared to the other sampling sites. A. phagocytophilum-DNA was detected in 2 bank voles, DNA of B. microti in 1 striped field-mouse and of Babesia sp. EU1 in the skin tissue of a mole. Co-infections were detected.
conclusionOur results show the involvement of small mammals in the natural endemic cycles of tick-borne pathogens. A more thorough understanding of the interactions of ticks, pathogens and hosts is the essential basis for effective preventive control measures.
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