ArticleDiabetes & metabolism journal2012
Severe hypoglycemia is a serious complication and becoming an economic burden in diabetes.
Article in Diabetes & metabolism journal, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Type I Diabetes Hypoglycemia Prevention Pilot Study
A Pilot Study of Nocturnal Hypoglycemia Prevention in Type 1 Diabetes Using the Vigilant Diabetes Management Companion
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.
- Magnitude, risk factors and economic impacts of diabetic emergencies in developing countries: A systematic review.PloS one · 2025Pooled it
- HypoAware-a brief and partly web-based psycho-educational group intervention for adults with type 1 and insulin-treated type 2 diabetes and problematic hypoglycaemia: design of a cost-effectiveness randomised controlled trial.BMC endocrine disorders · 2015Trial
- Financial burden of glycemic control: a single-center retrospective study of diabetes costs in South Korean patients.The Korean journal of internal medicine · 2026Article
- Incidence and influencing factors for hypoglycemia in maintenance hemodialysis patients with diabetic kidney disease: a meta-analysis.American journal of translational research · 2024Review
- The individualisation of glycaemic targets in response to patient characteristics in type 2 diabetes: a scoping review.Clinical medicine (London, England) · 2022Article
- Time in Range from Continuous Glucose Monitoring: A Novel Metric for Glycemic Control.Diabetes & metabolism journal · 2020Review
- Hazardous factors besides infection in hypoglycemia.Biomedical reports · 2017Article
- Dynamin-related protein 1 mediates low glucose-induced endothelial dysfunction in human arterioles.American journal of physiology. Heart and circulatory physiology · 2017Article
- Article
- Observational
- Economic Burden of Hypoglycemia in Patients with Type 2 Diabetes Mellitus from Korea.PloS one · 2016Article
- Intensive individualized reinforcement education is important for the prevention of hypoglycemia in patients with type 2 diabetes.Diabetes & metabolism journal · 2015Article
- 1,5-anhydroglucitol as a useful marker for assessing short-term glycemic excursions in type 1 diabetes.Diabetes & metabolism journal · 2015Article
- Association between hypoglycemia and fall-related events in type 2 diabetes mellitus: analysis of a U.S. commercial database.Journal of managed care & specialty pharmacy · 2015Article
- Causative anti-diabetic drugs and the underlying clinical factors for hypoglycemia in patients with diabetes.World journal of diabetes · 2015Review
- Avoiding or coping with severe hypoglycemia in patients with type 2 diabetes.The Korean journal of internal medicine · 2015Review
- Hypoglycemia in patients with type 1 diabetes: epidemiology, pathogenesis, and prevention.Current diabetes reports · 2013Review
- Severe hypoglycemia in patients with diabetes.Diabetes & metabolism journal · 2012Article
- Food Insecurity: A Concept Analysis.Nursing forumReview
- The Burden of Severe Hypoglycemia on Quality of Life among Diabetes Mellitus Patients in a Tertiary Level Hospital of Bangladesh.Indian journal of endocrinology and metabolismArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe prevalence of hypoglycemia is increasing due to the growing incidence of diabetes and the latest strict guidelines for glycated hemoglobin (HbA1c) levels under 7%. This study examined the clinical characteristics, causal factors, and medical costs of severely hypoglycemic patients in an emergency room (ER) of Uijeongbu St. Mary's Hospital.
methodsThe study consisted of a retrospective analysis of the characteristics, risk factors, and medical costs of 320 severely hypoglycemic patients with diabetes who presented to an ER of Uijeongbu St. Mary's Hospital from January 1, 2006 to December 31, 2009.
resultsMost hypoglycemic patients (87.5%, 280/320) were over 60 years old with a mean age of 69.5±10.9 years and a mean HbA1c level of 6.95±1.46%. Mean serum glucose as noted in the ER was 37.9±34.5 mg/dL. Renal function was decreased, serum creatinine was 2.0±2.1 mg/dL and estimated glomerular filtration rate (eGFR) was 48.0±33.6 mL/min/1.73 m(2). In addition, hypoglycemic patients typically were taking sulfonylureas or insulin and a variety of other medications, and had a long history of diabetes.
conclusionSevere hypoglycemia is frequent in older diabetic patients, subjects with low HbA1c levels, and nephropathic patients. Therefore, personalized attention is warranted, especially in long-term diabetics with multiple comorbidities who may not have been properly educated or may need re-education for hypoglycemia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.