ArticleAllergy, asthma & immunology research2012
The cockroach and allergic diseases.
Article in Allergy, asthma & immunology research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 83 citations in OpenAlex.
- Cockroach immunotherapy modulates dominant T-cell responses independent of allergen extract content.The Journal of allergy and clinical immunology · 2025Trial
- Indoor allergens and endotoxins in relation to cockroach infestations in low-income urban homes.The journal of allergy and clinical immunology. Global · 2026Article
- Inhalant Mediated Allergy: Immunobiology, Clinical Manifestations and Diagnosis.Clinical reviews in allergy & immunology · 2025Review
- Review
- Dissecting Airborne Allergens.Journal of clinical medicine · 2023Review
- Ampicillin treated German cockroach extract leads to reduced inflammation in human lung cells and a mouse model of Asthma.Parasites, hosts and diseases · 2023Article
- Study of Allergen Patterns in Cases of Moderate to Severe Persistent Allergic Rhinitis in Central India.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2022Article
- Allergen Management in Children with Type 2-High Asthma.Journal of asthma and allergy · 2022Review
- Effectiveness of Ethyl Formate as a Fumigant ofInsects · 2021Article
- Heterogeneity of magnitude, allergen immunodominance, and cytokine polarization of cockroach allergen-specific T cell responses in allergic sensitized children.Clinical and translational allergy · 2021Article
- Article
- Transcriptome Responses to Defined Insecticide Selection Pressures in the German Cockroach (Frontiers in physiology · 2021Article
- Reduced production of the major allergens Bla g 1 and Bla g 2 in Blattella germanica after antibiotic treatment.PloS one · 2021Article
- Activity of Vip3Aa1 againstOpen life sciences · 2020Article
- Rapid evolutionary responses to insecticide resistance management interventions by the German cockroach (Blattella germanica L.).Scientific reports · 2019Article
- German Cockroach Extract Induces Matrix Metalloproteinase-1 Expression, Leading to Tight Junction Disruption in Human Airway Epithelial Cells.Yonsei medical journal · 2018Article
- Mannose receptor modulates macrophage polarization and allergic inflammation through miR-511-3p.The Journal of allergy and clinical immunology · 2018Article
- Macrophage polarization and allergic asthma.Translational research : the journal of laboratory and clinical medicine · 2018Review
- N-glycan in cockroach allergen regulates human basophil function.Immunity, inflammation and disease · 2017Article
- Repellency of zerumbone identified in Cyperus rotundus rhizome and other constituents to Blattella germanica.Scientific reports · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The cockroach represents one of the most common sources of indoor allergens worldwide, and 40%-60% of patients with asthma in urban and inner-city areas possess IgE antibodies to cockroach allergens. In Korean homes, four cockroach species have been found, of which the most commonly encountered is the German cockroach. The pathogenic mechanism underlying the association between cockroach allergens and allergic diseases has not been fully elucidated. Allergenicity is associated with the cockroach allergens themselves, enzymatic protease activity, and ligands for pattern recognition receptors. Although allergen-specific adaptive immune responses orchestrate the cockroach allergic response, recent data suggest that the innate immune system is also a critical contributor to pathogenesis. We review the current evidence for the demographics of cockroach exposure and sensitization, characteristics of cockroach allergens, and inflammatory responses to cockroach allergens initiated through protease-dependent pathways.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.