ArticleInternational journal of molecular sciences2012
Comparative characterization of total flavonol glycosides and terpene lactones at different ages, from different cultivation sources and genders of Ginkgo biloba leaves.
Article in International journal of molecular sciences, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 44 citations in OpenAlex.
- Ginkgo biloba extract improved cognitive and neurological functions of acute ischaemic stroke: a randomised controlled trial.Stroke and vascular neurology · 2017Trial
- Physiological and molecular regulatory mechanisms of flavonoid and hormone biosynthesis in rejuvenated the oldest ginkgo tree.BMC genomics · 2025Article
- Metabolomic and transcriptomic analyses unveil the accumulation of shikimic acid in the leaves ofFrontiers in plant science · 2025Article
- Hyperspectral Imaging Combined with Deep Transfer Learning to Evaluate Flavonoids Content inInternational journal of molecular sciences · 2024Article
- Medicinal Values and Potential Risks Evaluation ofMolecules (Basel, Switzerland) · 2022Article
- A Comparison of the Flavonoid Biosynthesis Mechanisms ofInternational journal of molecular sciences · 2022Article
- Review
- Multi-Response Optimization of Ultrasonic Assisted Enzymatic Extraction Followed by Macroporous Resin Purification for Maximal Recovery of Flavonoids and Ginkgolides from WasteMolecules (Basel, Switzerland) · 2018Article
- Novel analysis of maturation of murine bone-marrow-derived dendritic cells induced by Ginkgo Seed Polysaccharides.Human vaccines & immunotherapeutics · 2015Article
- A ginkgo biloba extract promotes proliferation of endogenous neural stem cells in vascular dementia rats.Neural regeneration research · 2013Article
- A UPLC-MS/MS method for qualification of quercetin-3-O-β-D-glucopyranoside-(4→1)-α-L-rhamnoside in rat plasma and application to pharmacokinetic studies.Molecules (Basel, Switzerland) · 2013Article
- Comparative analysis of the main bioactive components of San-ao decoction and its series of formulations.Molecules (Basel, Switzerland) · 2012Article
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The extract from Ginkgo biloba leaves has become a very popular plant medicine and herbal supplement for its potential benefit in alleviating symptoms associated with peripheral vascular disease, dementia, asthma and tinnitus. Most research on G. biloba leaves focus on the leaves collected in July and August from four to seven year-old trees, however a large number of leaves from fruit cultivars (trees older than 10 years) are ignored and become obsolete after fruit harvest season (November). In this paper, we expand the tree age range (from one to 300 years) and first comparatively analyze the total flavonol glycosides and terpene lactones at different ages, from different cultivation sources and genders of G. biloba leaves collected in November by using the validated HPLC-ELSD and HPLC-PDA methods. The results show that the contents of total terpene lactones and flavonol glycosides in the leaves of young ginkgo trees are higher than those in old trees, and they are higher in male trees than in female trees. Geographical factors appear to have a significant influence on the contents as well. These results will provide a good basis for the comprehensive utilization of G. biloba leaves, especially the leaves from fruit cultivars.
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