Evidence map›Paper›PMID 22949838›Full record

ReviewInternational journal of molecular sciences2012

Molecular mechanisms of epigenetic variation in plants.

Ryo Fujimoto, Taku Sasaki, Ryo Ishikawa, Kenji Osabe, Takahiro Kawanabe, Elizabeth S Dennis

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 71 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Roles of methyl-CpG-binding-domain (MBD) protiens in regulation of biological processes in plants.Physiology and molecular biology of plants : an international journal of functional plant biology · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Classification of CRISPR/Cas system and its application in tomato breeding.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022
    Review
  10. Will epigenetics be a key player in crop breeding?Frontiers in plant science · 2022
    Review
  11. Whole-Genome DNA Methylation Analysis inFrontiers in plant science · 2022
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Review
  18. The histone modification H3 lysine 27 tri-methylation has conserved gene regulatory roles in the triplicated genome of Brassica rapa L.DNA research : an international journal for rapid publication of reports on genes and genomes · 2019
    Article
  19. Towards Exploitation of Adaptive Traits for Climate-Resilient Smart Pulses.International journal of molecular sciences · 2019
    Review
  20. Genome-wide characterization of DNA methylation, small RNA expression, and histone H3 lysine nine di-methylation in Brassica rapa L.DNA research : an international journal for rapid publication of reports on genes and genomes · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 4 countries.

Ryo FujimotoGraduate School of Science and Technology, Niigata University, Nishi-ku, Niigata 950-2181, Japan.
Taku SasakiGregor Mendel Institute of Molecular Plant Biology, Austrian Academy of Sciences, Dr. Bohrgasse 3, Vienna 1030, Austria.
Ryo IshikawaLaboratory of Plant Breeding, Graduate School of Agricultural Science, Kobe University, Nada, Kobe 657-8510, Japan.
Kenji OsabeCommonwealth Scientific and Industrial Research Organisation (CSIRO) Plant Industry, Canberra ACT 2601, Australia.
Takahiro KawanabeWatanabe Seed Co., Ltd, Machiyashiki, Misato-cho, Miyagi 987-8607, Japan.
Elizabeth S DennisCommonwealth Scientific and Industrial Research Organisation (CSIRO) Plant Industry, Canberra ACT 2601, Australia.
Commonwealth Scientific and Industrial Research Organisation · AUAustrian Academy of Sciences · ATNiigata University · JPNorwich Research Park · GBSakurabashi Watanabe Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural variation is defined as the phenotypic variation caused by spontaneous mutations. In general, mutations are associated with changes of nucleotide sequence, and many mutations in genes that can cause changes in plant development have been identified. Epigenetic change, which does not involve alteration to the nucleotide sequence, can also cause changes in gene activity by changing the structure of chromatin through DNA methylation or histone modifications. Now there is evidence based on induced or spontaneous mutants that epigenetic changes can cause altering plant phenotypes. Epigenetic changes have occurred frequently in plants, and some are heritable or metastable causing variation in epigenetic status within or between species. Therefore, heritable epigenetic variation as well as genetic variation has the potential to drive natural variation.

Indexed as

Gene Expression Regulation, PlantGenetic VariationEpigenesis, GeneticGenome, PlantPlant Physiological PhenomenaPlantsDNA methylationepigeneticmetastablenatural variation

Identifiers

PMID22949838
PMCPMC3431836
OpenAlexW2010345053

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.