Evidence map›Paper›PMID 22949828›Full record

ArticleInternational journal of molecular sciences2012

Constituents from Vigna vexillata and their anti-inflammatory activity.

Yann-Lii Leu, Tsong-Long Hwang, Ping-Chung Kuo, Kun-Pei Liou, Bow-Shin Huang, Guo-Feng Chen

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Euphormins A and B, New Pyranocoumarin Derivatives fromMolecules (Basel, Switzerland) · 2022
    Article
  5. Review
  6. Revisiting the Domestication Process of AfricanPlants (Basel, Switzerland) · 2022
    Review
  7. Article
  8. Flavonoids as inhibitors of human neutrophil elastase.Journal of enzyme inhibition and medicinal chemistry · 2021
    Review
  9. Chemical Constituents ofMolecules (Basel, Switzerland) · 2019
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yann-Lii LeuGraduate Institute of Natural Products, Chang Gung University, Taoyuan 333, Taiwan.
Tsong-Long HwangGraduate Institute of Natural Products, Chang Gung University, Taoyuan 333, Taiwan.ORCID 0000-0002-5780-3977
Ping-Chung KuoDepartment of Biotechnology, National Formosa University, Yunlin 632, Taiwan.
Kun-Pei LiouDepartment of Biotechnology, National Formosa University, Yunlin 632, Taiwan.
Bow-Shin HuangDepartment of Biotechnology, National Formosa University, Yunlin 632, Taiwan.
Guo-Feng ChenDepartment of Chemistry, National Chung-Hsing University, Taichung 402, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The seeds of Vigna genus are important food resources and there have already been many reports regarding their bioactivities. In our preliminary bioassay, the chloroform layer of methanol extracts of V. vexillata demonstrated significant anti-inflammatory bioactivity. Therefore, the present research is aimed to purify and identify the anti-inflammatory principles of V. vexillata. One new sterol (1) and two new isoflavones (2,3) were reported from the natural sources for the first time and their chemical structures were determined by the spectroscopic and mass spectrometric analyses. In addition, 37 known compounds were identified by comparison of their physical and spectroscopic data with those reported in the literature. Among the isolates, daidzein (23), abscisic acid (25), and quercetin (40) displayed the most significant inhibition of superoxide anion generation and elastase release.

Indexed as

AdultAnti-Inflammatory AgentsFabaceaeHumansMolecular StructureNeutrophilsPancreatic ElastaseSeedsSuperoxidesYoung AdultAnti-Inflammatory AgentsPancreatic ElastaseSuperoxidesanti-inflammatoryelastaseisoflavonesuperoxide anionVigna

Identifiers

PMID22949828
PMCPMC3431826

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.