SynthesisClinical orthopaedics and related research2013
Computer-assisted total knee arthroplasty is currently of no proven clinical benefit: a systematic review.
Synthesis in Clinical orthopaedics and related research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
61 citing papers in PubMed, 3 syntheses or guidelines pooled it, 147 citations in OpenAlex.
- Does Accelerometer-based Navigation Have Any Clinical Benefit Compared with Conventional TKA? A Systematic Review.Clinical orthopaedics and related research · 2019Pooled it
- Systematic review of patient-specific instrumentation in total knee arthroplasty: new but not improved.Clinical orthopaedics and related research · 2015Pooled it
- Does imageless computer-assisted TKA lead to improved rotational alignment or fewer outliers? A systematic review.Clinical orthopaedics and related research · 2014Pooled it
- No clinical difference between TiN-coated versus uncoated cementless CoCrMo mobile-bearing total knee arthroplasty; 10-year follow-up of a randomized controlled trial.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2021Trial
- Patient-specific instrumentation in total knee arthroplasty: simpler, faster and more accurate than standard instrumentation-a randomized controlled trial.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2017Trial
- Alignment of the lower extremity mechanical axis by computer-aided design and application in total knee arthroplasty.International journal of computer assisted radiology and surgery · 2016Trial
- Intra- and post-operative accuracy assessments of two different patient-specific instrumentation systems for total knee replacement.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2014Trial
- No difference between computer-assisted and conventional total knee arthroplasty: five-year results of a prospective randomised study.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2013Trial
- Short-term Outcomes of Unrestricted Kinematic Alignment: Total Knee Arthroplasty With a Medial Pivot Implant: A Japanese Multicenter Study.Arthroplasty today · 2026Article
- What Are the Game Changers in Total Knee Arthroplasty? A Narrative Review.Journal of personalized medicine · 2025Review
- There Is a Difference in Patients' Opinions and Scientific Evidence Regarding Robot Assisted Total Joint Arthroplasty: a Questionnaire.Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca · 2025Article
- Navigation Assistance in Orthopedic Oncosurgery: Our Early Experience.Indian journal of surgical oncology · 2025Article
- Progress in Computer-Assisted Navigation for Total Knee Arthroplasty in Treating Knee Osteoarthritis with Extra-Articular Deformity.Orthopaedic surgery · 2024Review
- No Difference in Clinical Outcomes and Survivorship for Robotic, Navigational, and Conventional Primary Total Knee Arthroplasty with a Minimum Follow-up of 10 Years.Clinics in orthopedic surgery · 2023Article
- Time is Money! Influence on Operating Theater and Sterilization Times of Patient-specific Cutting Guides and Single-use Instrumentation for Total Knee Arthroplasty: A Full Factorial Design of 136 Patients.Arthroplasty today · 2022Article
- [Future implications of navigation in total knee arthroplasty].Orthopadie (Heidelberg, Germany) · 2022Review
- The successful implementation of the Navio robotic technology required 29 cases.Journal of robotic surgery · 2022Article
- Pros and cons of navigated versus conventional total knee arthroplasty-a retrospective analysis of over 2400 patients.Archives of orthopaedic and trauma surgery · 2021Article
- No difference in long-term functional outcomes or survivorship after total knee arthroplasty with or without computer navigation: a 17-year survivorship analysis.Knee surgery & related research · 2021Article
- Efficacy Analysis of Selection of Distal Reference Point for Tibial Coronal Plane Osteotomy during Total Knee Arthroplasty: A Literature Review.Orthopaedic surgery · 2021Review
1 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNavigated total knee arthroplasty (TKA) may improve coronal alignment outliers; however, it is unclear whether navigated TKA improves the long-term clinical results of TKA. QUESTIONS/PURPOSES: Does the literature contain evidence of better long-term function and lower revision rates with navigated TKA compared with conventional TKA?
methodsA systematic literature review was conducted of navigated TKA reviewing articles related to coronal alignment, clinical knee and function scores, cost, patient satisfaction, component rotation, anteroposterior and mediolateral stability, complications, and longer-term reports.
resultsCoronal plane alignment is improved with navigated TKA with fewer radiographic outliers. We found limited evidence of improvements in any other variable, and function was not improved. The duration of surgery is increased and there are unique complications related to navigated TKA. The long-term benefits of additional increase in accuracy of alignment are not supported by any current evidence.
conclusionsThe findings in reports of navigated TKA should be interpreted with caution. There are few short- and medium- and no long-term studies demonstrating improved clinical outcomes using navigated TKA. Despite substantial research, contradictory findings coupled with reservations about the cost and efficacy of the technology have contributed to the failure of computer navigation to become the accepted standard in TKA. Longer-term studies demonstrating improved function, lower revision rates, and acceptable costs are required before navigated TKA may be widely adopted. In the future, with improvements in study design, methodology, imaging, navigation technology, newer functional outcome tools, and longer-term followup studies, we suspect that navigated TKA may demonstrate yet unrecognized benefits.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.