ArticleTransgenic research2013
Co-expression of AtbHLH17 and AtWRKY28 confers resistance to abiotic stress in Arabidopsis.
Article in Transgenic research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers, 1 of them a synthesis that pooled it.
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Who cites it
87 citing papers in PubMed, 1 synthesis or guideline pooled it, 200 citations in OpenAlex.
- Transcriptomic responses under combined bacterial blight and drought stress in rice reveal potential genes to improve multi-stress tolerance.BMC plant biology · 2022Pooled it
- A Truncated WRKY Protein Enhances Drought Resistance in Wild Tomatoes Through the SlWRKY16-CIP2b-SlSYP121 Module.Plant biotechnology journal · 2026Article
- Genome-wide identification and functional characterization of bHLH transcription factors in Herpetospermum pedunculosum under salt stress.BMC plant biology · 2026Article
- Pangenome-Wide Identification, Evolutionary Analysis of Maize ZmPLD Gene Family, and Functional Validation of ZmPLD15 in Cold Stress Tolerance.Plants (Basel, Switzerland) · 2025Article
- Comprehensive analysis of bHLH transcription factors reveals candidate regulators of flower development and heat stress response in Rhododendron simsii.BMC plant biology · 2025Article
- Plant Signaling Hormones and Transcription Factors: Key Regulators of Plant Responses to Growth, Development, and Stress.Plants (Basel, Switzerland) · 2025Review
- Comprehensive genomic analysis of SmbHLH genes and the role of SmbHLH93 in eggplant anthocyanin biosynthesis.Plant cell reports · 2025Article
- The StbHLH47 transcription factor negatively regulates drought tolerance in potato (Solanum tuberosum L.).BMC plant biology · 2025Article
- Unlocking ABA's role in rice cold tolerance: insights from Zhonghua 11 and Kasalath.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Studies on the Physiological Response ofInternational journal of molecular sciences · 2024Article
- Small chemical molecules regulating the phytohormone signalling alter the plant's physiological processes to improve stress adaptation, growth and productivity.Physiology and molecular biology of plants : an international journal of functional plant biology · 2024Review
- WRKY Transcription Factor Responses and Tolerance to Abiotic Stresses in Plants.International journal of molecular sciences · 2024Review
- Proteomic profiling ofPhysiology and molecular biology of plants : an international journal of functional plant biology · 2024Article
- De novo transcriptomic analysis of Doum Palm (Hyphaene compressa) revealed an insight into its potential drought tolerance.PloS one · 2024Article
- Multi-omics analysis of hexaploid triticale that show molecular responses to salt stress during seed germination.Frontiers in plant science · 2024Article
- Genome-wide identification and expression analysis of bHLH gene family revealed their potential roles in abiotic stress response, anthocyanin biosynthesis and trichome formation inFrontiers in plant science · 2024Article
- Genome-Wide Characterization ofPlants (Basel, Switzerland) · 2023Article
- Functional Study ofInternational journal of molecular sciences · 2023Article
- Genome-wide identification of SrbHLH transcription factors highlights its potential role in rebaudioside A (RA) biosynthesis in Stevia rebaudiana.BMC plant biology · 2023Article
- Transcriptional and Post-Translational Regulation of Plant bHLH Transcription Factors during the Response to Environmental Stresses.Plants (Basel, Switzerland) · 2023Review
27 more citing papers are in PubMed but not listed here.
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Stress adaptation in plants involves altered expression of many genes through complex signaling pathways. To achieve the optimum expression of downstream functional genes, we expressed AtbHLH17 (AtAIB) and AtWRKY28 TFs which are known to be upregulated under drought and oxidative stress, respectively in Arabidopsis. Multigene expression cassette with these two TFs and reporter gene GUS was developed using modified gateway cloning strategy. The GUS assay and expression analysis of transgenes in transgenic plants confirmed the integration of multigene cassette. The transgenic lines exhibited enhanced tolerance to NaCl, Mannitol and oxidative stress. Under mannitol stress condition significantly higher root growth was observed in transgenics. Growth under stress and recovery growth was substantially superior in transgenics exposed to gradual long term desiccation stress conditions. We demonstrate the expression of several downstream target genes under various stress conditions. A few genes having either WRKY or bHLH cis elements in their promoter regions showed higher transcript levels than wild type. However, the genes which did not have either of the motifs did not differ in their expression levels in stress conditions compared to wild type plants. Hence co-expressing two or more TFs may result in upregulation of many downstream target genes and substantially improve the stress tolerance of the plants.
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